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Claudin-2 enhances human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells by modulating antibody binding and complement activation. [PDF]
Li W+14 more
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Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation. [PDF]
Busa D+13 more
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Antibody‐mediated rejection in xenotransplantation: Can it be prevented or reversed?
Xenotransplantation, 2023Antibody‐mediated rejection (AMR) is the commonest cause of failure of a pig graft after transplantation into an immunosuppressed nonhuman primate (NHP). The incidence of AMR compared to acute cellular rejection is much higher in xenotransplantation (46%
Z. Habibabady+10 more
semanticscholar +1 more source
Attitudes of patients with renal disease on xenotransplantation: A systematic review
Xenotransplantation, 2023Recent years have seen major advancements in xenotransplantation: the first pig‐to‐human heart transplant, the development of a brain‐dead recipient model for kidney xenotransplantation, and the registration of the first xenokidney clinical trial.
I. DeLaura+5 more
semanticscholar +1 more source
Acceptance of xenotransplantation by patients waiting for organ donation: A qualitative study
Xenotransplantation, 2023The aim of this study was to determine the acceptance and barriers to xenotransplantation in patients waiting for organ transplantation.
özlem şahin akboğa+1 more
semanticscholar +1 more source
The porcine cytomegalovirus (PCMV) will not stop xenotransplantation
Xenotransplantation, 2022During the first pig heart xenotransplantation into a human patient at the University of Maryland in Baltimore, a pig virus was transmitted to the patient.
J. Denner
semanticscholar +1 more source
Annual Review of Medicine, 1995
▪ Abstract The need for an alternative source of donor organs, together with the expansion of scientific data in this field, has focused attention on xenotransplantation as a possible alternative to allotransplantation in the treatment of patients with end-stage disease of vital organs. However, xenotransplantation is rarely successful.
D J, Steele, H, Auchincloss
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▪ Abstract The need for an alternative source of donor organs, together with the expansion of scientific data in this field, has focused attention on xenotransplantation as a possible alternative to allotransplantation in the treatment of patients with end-stage disease of vital organs. However, xenotransplantation is rarely successful.
D J, Steele, H, Auchincloss
openaire +4 more sources
The FASEB Journal, 1994
Transplantation of solid organs (heart, lung, liver, and kidney) from swine to humans would solve the current critical shortage of cadaver organs needed by patients with end-stage disease of these organs. In addition, transplantation between distant species (discordant xenografting) will require an understanding of a number of unique immunologic ...
C Y, Lu+6 more
openaire +2 more sources
Transplantation of solid organs (heart, lung, liver, and kidney) from swine to humans would solve the current critical shortage of cadaver organs needed by patients with end-stage disease of these organs. In addition, transplantation between distant species (discordant xenografting) will require an understanding of a number of unique immunologic ...
C Y, Lu+6 more
openaire +2 more sources
Xenotransplantation, 2022
Some clinical trials have shown the usefulness of stem cell therapy for diabetic foot ulcers. However, the donor supply is limited, and the process is time consuming and expensive.
Hideaki Yamada+12 more
semanticscholar +1 more source
Some clinical trials have shown the usefulness of stem cell therapy for diabetic foot ulcers. However, the donor supply is limited, and the process is time consuming and expensive.
Hideaki Yamada+12 more
semanticscholar +1 more source