Results 81 to 90 of about 46,793 (276)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Exact solution of a variety of X-ray probes in the Falicov-Kimball model with dynamical mean-field theory

Condensed Matter Physics, 2012
We examine the core-level X-ray photoemission spectroscopy (XPS), X-ray absorption near-edge spectroscopy (XANES) and X-ray emission spectroscopy (XES) in the Falicov-Kimball model by using the exact solution from dynamical mean-field theory.
A.M. Shvaika, J.K. Freericks
doaj   +1 more source

Visualization of elemental distributions and local analysis of element-specific chemical states of an Arachnoidiscus sp. frustule using soft X-ray spectromicroscopy.

PLoS ONE, 2020
Using soft X-ray (SX) spectromicroscopy, we show maps of the spatial distribution of constituent elements and local analysis of the density of states (DOS) related to the element-specific chemical states of diatom frustules, which are composed of ...
Tomoko Ishihara, Takuo Ohkochi, Akinobu Yamaguchi, Yoshinori Kotani, Masaki Oura   +4 more
doaj   +1 more source

Multiconfigurational nature of 5f orbitals in uranium and plutonium intermetallics

, 2012
Uranium and plutonium's 5f electrons are tenuously poised between strongly bonding with ligand spd-states and residing close to the nucleus. The unusual properties of these elements and their compounds (eg.
Bauer, C. H. Booth, Conradson, D. L. Wang, D. Nordlund, D. Sokaras, Dallera, E. D. Bauer, J. L. Sarrao, J. N. Mitchell, Lashley, Lawrence, M. A. Torrez, M. A. Wall, P. G. Allen, P. H. Tobash, Palstra, Sarrao, Sato, Shim, T.- C. Weng, Y. Jiang   +21 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Evidence for weak electronic correlations in Fe-pnictides

, 2009
Using x-ray absorption and resonant inelastic x-ray scattering, charge dynamics at and near the Fe $L$ edges is investigated in Fe pnictide materials, and contrasted to that measured in other Fe compounds.
Analytis, J.,, Chen, C-C, Chen, C-C., Chu, J.-H, Delley, B., Denlinger, J.,, Devereaux, P., Devereaux, T,, Fisher, I.,, Hussain, Z., Lee, W.-S, Lu, W., Moritz, B., Olalde-Velasco, P., Ren, A., Ren, Z,, Shen, Z.-X, Sorini, A.,, van den Brink, J., Vernay, F., Yang, J., Yang, W.,, Zhao, Z.,   +22 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Electronic Structure and Valence Band Spectra of Bi4Ti3O12

, 1995
The x-ray photoelectron valence band spectrum and x-ray emission valence-band spectra (Ti K _beta_5, Ti L_alpha, O K_alpha) of Bi4Ti3O12 are presented (analyzed in the common energy scale) and interpreted on the basis of a band-structure calculation for ...
A. David Rae, A. V. Postnikov, B. Aurivillius, B. Aurivillius, B. Aurivillius, B. Frit, B. T. Matthias, D. C. Langreth, D. C. Langreth, E. C. Subbarao, E. Takayama Muromachi, E. Z. Kurmaev, F. Mersch, G. A. Smolenskii, H. Maeda, J. F. Dorrian, K. Okada, M. Neumann, M. Takashige, N. I. Medvedeva, O. K. Andersen, O. K. Andersen, R. E. Cohen, R. E. Cohen, S. N. Nemnonov, St. Bartkowski, T. M. Burton, T. Uozumi, U. Schönberger, U. von Barth, V. E. Dolgih, V. M. Cherkashenko, V. R. Galakhov, W. Jo, W. Jo, W. Zhong   +35 more
core   +1 more source