Results 191 to 200 of about 618,994 (277)

Chondroitin sulfate restores muscle mass via gut–muscle axis remodeling through sugar–bile acid metabolism reprogramming

open access: yesiMeta, EarlyView.
The graphical abstract illustrates the molecular mechanism by which chondroitin sulfate (DCS) alleviates glucocorticoid‐induced myopathy through the gut–muscle axis. DCS selectively enriches L. johnsonii Z‐RW, enhancing bshA‐encoded BSH activity to promote bile acid deconjugation and reduce the sugar–bile acid ratio, thereby re‐establishing intestinal ...
Ruiyun Wu   +7 more
wiley   +1 more source

Body composition at 2 years of age in moderate and late preterm infants

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Moderate and late preterm infants (MLPTI, gestational age 32 0/7–36 6/7 weeks) have altered body composition compared to term‐born infants, but data beyond infancy are lacking. This study aimed to assess body composition at 2 years corrected age for prematurity (CA) in MLPTI, compare it to the literature on term‐born infants, and ...
Anne H. Lafeber   +6 more
wiley   +1 more source

Long‐Term Clinical Response After Low‐Dose and Short‐Duration Cemiplimab Therapy in a Patient With Xeroderma Pigmentosum in Nepal

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Xeroderma pigmentosum (XP), an autosomal recessive condition affecting DNA repair, is associated with a high risk of multiple and aggressive cutaneous squamous cell carcinomas (CSCCs). Because of numerous and/or locally advanced tumors, surgery may be difficult.
Sudip Parajuli   +5 more
wiley   +1 more source

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen   +4 more
wiley   +1 more source

A Large and Precise All-Sky Photometric Standard Star Dataset Across More Than 200 Passbands. [PDF]

open access: yesSci Data
Xiao K   +14 more
europepmc   +1 more source

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng   +8 more
wiley   +1 more source

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