Results 31 to 40 of about 618,994 (277)

New Explicit Lorentzian Einstein-Weyl Structures in 3-Dimensions [PDF]

, 2020
On a $3$D manifold, a Weyl geometry consists of pairs $(g, A) =$ (metric, $1$-form) modulo gauge $\widehat{g} = {\rm e}^{2\varphi} g$, $\widehat{A} = A + {\rm d}\varphi$.
Merker, Joël, Nurowski, Paweł
core   +2 more sources

Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert® MTB/RIF era: a cohort study

BMC Infectious Diseases, 2017
Background The Xpert® MTB/RIF (XP) has a higher sensitivity than sputum smear microscopy (70% versus 35%) for TB diagnosis and has been endorsed by the WHO for TB high burden countries to increase case finding among HIV co-infected presumptive TB ...
Sabine M. Hermans, Juliet A. Babirye, Olive Mbabazi, Francis Kakooza, Robert Colebunders, Barbara Castelnuovo, Christine Sekaggya-Wiltshire, Rosalind Parkes-Ratanshi, Yukari C. Manabe   +8 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Whole-Exome Sequencing Enables Rapid Determination of Xeroderma Pigmentosum Molecular Etiology [PDF]

, 2013
Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder haracterized by extreme sensitivity to actinic pigmentation changes in the skin and increased incidence of skin cancer. In some cases, patients are affected by neurological alterations. XP
Bermúdez, Olga, Fonseca-Mendoza, Dora Janeth, Ine´s Vergara, Jéssica, Laissue, Paul, Medina, Claudia Liliana, Mosquera, Hernando, Ortega-Recalde, Oscar-Javier, Pallares, Argemiro Enrique, Restrepo, Carlos Martín, Ríos, Xiomara, Vargas, Clara   +10 more
core   +2 more sources

Antibacterial activity of marine bacteria isolated from sponge Xestospongia testudinaria from Sorong, Papua

Asian Pacific Journal of Tropical Biomedicine, 2017
Objective: To explore secondary metabolite of bacteria-associated Xestospongia testudinaria from Tanjung Kasuari, Sorong, Papua. Methods: The antimicrobial activities of extracts against two Gram-positive bacteria (Staphylococcus aureus) and three Gram ...
Yatnita Parama Cita, Achmad Suhermanto, Ocky Karna Radjasa, Pratiwi Sudharmono   +3 more
doaj   +1 more source

XPC and POLH/XPV Genes Mutated in a Genetic Cluster of Xeroderma Pigmentosum Patients in Northeast Brazil

Frontiers in Genetics, 2022
Xeroderma pigmentosum (XP) is a rare genetic condition in which exposure to sunlight leads to a high tumor incidence due to defective DNA repair machinery.
Ligia Pereira Castro, Danilo Batista-Vieira, Tiago Antonio de Souza, Ana Rafaela de Souza Timoteo, Jessica Dayanna Landivar Coutinho, Isabel Cristina Pinheiro de Almeida, Sheila Ramos de Miranda Henriques, Fabio Medeiros de Azevedo, Reginaldo Cruz Alves Rosa, Reginaldo Cruz Alves Rosa, Patricia L Kannouche, Alain Sarasin, Carlos Frederico Martins Menck, Tirzah Braz Petta, Tirzah Braz Petta, Tirzah Braz Petta, Tirzah Braz Petta   +16 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Scaling the Management of Extreme Programming Projects [PDF]

, 2014
XP is a code-oriented, light-weight software engineering methodology, suited merely for small-sized teams who develop software that relies on vague or rapidly changing requirements. Being very code-oriented, the discipline of systems engineering knows it
Rumpe, Bernhard, Scholz, Peter
core  

Framing automation of driving tasks: Effects on risk perception and consumers’ understanding of different levels of vehicle automation across four European countries

IATSS Research
Framing is the process whereby people's perception is influenced by how information is presented. In the automotive sector, well-known frames concern the names for advanced driver assistance systems (ADAS) which suggest higher levels of automation (e.g.,
Ilse M. Harms, Wouter Van den Berghe
doaj   +1 more source