Results 11 to 20 of about 1,113 (188)

Superior Stability of Hydroxysafflor Yellow A in Xuebijing Injection and the Associated Mechanism [PDF]

Molecules, 2017
Hydroxysafflor yellow A (HSYA) is the main bioactive ingredient of XBJ injection. At first, the stability of HSYA in solution and in a Xuebijing injection was investigated, then the mechanisms of the increased stability of HSYA in the XBJ injection were ...
Weiling Pu, Huijie Zhang, Meng Wang, Yanan Liu, Lili Sun, Xiaoliang Ren   +5 more
doaj   +4 more sources

Exploring the Mechanism of Action of Xuebijing Injection in Treating Acute Respiratory Distress Syndrome Based on Network Pharmacology and Animal Experiments [PDF]

Journal of Inflammation Research
Jin Li,1,* Meirong Shen,2,* Zuan Yin3 1Department of Intensive Care Unit, The Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang City, Jiangxi Province, 330006, People’s Republic of China; 2Department of Intensive ...
Li J, Shen M, Yin Z
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The protective effects of Xuebijing injection on intestinal injuries of mice exposed to irradiation

Animal Models and Experimental Medicine, 2022
Background Gastrointestinal (GI) injury is one of the most common side effects of radiotherapy. However, there is no ideal therapy method except for symptomatic treatment in the clinic.
Yinping Dong, YuanYang Zhang, Xinyue Wang, Wenxuan Li, Junling Zhang, Lu Lu, Hui Dong, Saijun Fan, Aimin Meng, Deguan Li   +9 more
doaj   +4 more sources

Paeoniflorin and Hydroxysafflor Yellow A in Xuebijing Injection Attenuate Sepsis-Induced Cardiac Dysfunction and Inhibit Proinflammatory Cytokine Production

Frontiers in Pharmacology, 2021
Sepsis-induced myocardial dysfunction is a major contributor to the poor outcomes of septic shock. As an add-on with conventional sepsis management for over 15 years, the effect of Xuebijing injection (XBJ) on the sepsis-induced myocardial dysfunction ...
Xin-Tong Wang, Xin-Tong Wang, Zhen Peng, Zhen Peng, Ying-Ying An, Ying-Ying An, Ting Shang, Ting Shang, Guangxu Xiao, Guangxu Xiao, Shuang He, Shuang He, Xi Chen, Han Zhang, Yuefei Wang, Tao Wang, Jun-Hua Zhang, Xiumei Gao, Yan Zhu, Yan Zhu, Yuxin Feng, Yuxin Feng   +21 more
doaj   +3 more sources

Microcirculatory Disorders and Protective Role of Xuebijing in Severe Heat Stroke

Scientific Reports, 2018
AbstractThis study was conducted to explore underlying mechanism of microcirculation dysfunction and protectiverole of Xuebijing in heat stroke. Forty rats were divided into: control, vehicle + heat stress (HS), superoxide dismutase (SOD) + HS, and Xuebijing + HS groups.
Jin, Hui, Chen, Yi, Ding, Chengjia, Lin, Youping, Chen, Yulan, Jiang, Dongxin, Su, Lei   +6 more
openaire   +3 more sources

Efficacy and safety of Xuebijing injection for radiation pneumonitis: A meta-analysis

PLoS ONE, 2022
Background Currently, the treatment of radiation pneumonitis (RP) remains a clinical challenge. Although glucocorticoids are used for RP treatment, they have associated side effects.
Zheng Li, Dandan Wang, Ying Zhang, Shuo Wang, Xueqian Wang, Yuxiao Li, Yuerong Gui, Jun Dong, Wei Hou   +8 more
doaj   +4 more sources

Treatment effects of Xuebijing injection in patients with sepsis by clinical phenotype: a post hoc analysis of the EXIT-SEP trialResearch in context [PDF]

EClinicalMedicine
Summary: Background: Xuebijing injection (XBJ) could improve the outcomes of sepsis patients. However, sepsis is a heterogeneous syndrome, and it remains unclear which patients benefit the most.
Xiran Lou, Hui Chen, Nan Shi, Ruixuan Yu, Songli Li, Yi Yang, Songqiao Liu, Jianfeng Xie, Haibo Qiu   +8 more
doaj   +2 more sources

Different traditional Chinese medicine injections combined with conventional therapy for sepsis-induced myocardial dysfunction: a systematic review and network meta-analysis [PDF]

Frontiers in Pharmacology
ObjectiveAs the use of Traditional Chinese Medicine injections (TCMIs) for sepsis-induced myocardial dysfunction (SIMD) becomes increasingly diverse, this study aims to evaluate their efficacy, optimal combinations, and safety.MethodsA comprehensive ...
Wenjie Deng, Xiaolei Fang, Po Huang
doaj   +2 more sources

Integrated Transcriptomic, Proteomic, and Network Pharmacology Analyses Unravel Key Therapeutic Mechanisms of Xuebijing Injection for Severe Acute Pancreatitis [PDF]

Pharmaceuticals
Background: Xuebijing Injection (XBJ), a plant-derived traditional Chinese medicine administered as an injection, is widely used in clinical practice to treat various acute critical illnesses including severe acute pancreatitis (SAP).
Linbo Yao, Xinmin Yang, Mei Yuan, Shiyu Liu, Qiqi Wang, Yongzi Wu, Wenjuan Luo, Xueying Wu, Wenhao Cai, Lan Li, Ziqi Lin, Juqin Yang, Tingting Liu, Robert Sutton, Peter Szatmary, Tao Jin, Qing Xia, Wei Huang   +17 more
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Comprehensive integration of diagnostic biomarker analysis and immune cell infiltration features in sepsis via machine learning and bioinformatics techniques [PDF]

Frontiers in Immunology
IntroductionSepsis, a critical medical condition resulting from an irregular immune response to infection, leads to life-threatening organ dysfunction.
Liuqing Yang, Liuqing Yang, Liuqing Yang, Rui Xuan, Rui Xuan, Rui Xuan, Dawei Xu, Dawei Xu, Dawei Xu, Aming Sang, Aming Sang, Aming Sang, Jing Zhang, Jing Zhang, Jing Zhang, Yanfang Zhang, Xujun Ye, Xinyi Li, Xinyi Li, Xinyi Li   +19 more
doaj   +2 more sources