Results 21 to 30 of about 1,113 (188)

Xuebijing injection mitigates instant blood−mediated inflammatory reaction and enhances intrahepatic islet transplantation via target NF−κB pathway [PDF]

Frontiers in Immunology
IntroductionInstant blood-mediated inflammatory reaction (IBMIR) is a major obstacle in clinical islet transplantation, leading to islet apoptosis and dysfunction due to inflammatory reaction.
Yixiang Zhan, Yingbo Wang, Boya Zhang, Yijun Zhang, Rui Liang, Jiuxia Yang, Tengli Liu, Xiaoyan Hu, Tianyi You, Na Liu, Yuqi Chen, Qing Liu, Tingsheng Jiang, Zhaoce Liu, Xiangheng Cai, Runnan Yang, Yingyi Qi, Peng Sun, Jiaqi Zou, Xuejie Ding, Zhuzeng Yin, Shusen Wang   +21 more
doaj   +2 more sources

Xuebijing enhances antitumor efficacy of anti-CD19 CAR-T cells

Journal of Traditional Chinese Medical Sciences
Objective: To investigate the effects and mechanisms of Xuebijing injection (XBJ) on Chimeric antigen receptor-T (CAR-T) cell function and its therapeutic potential against CAR-T therapy-associated cytokine storms (CRS).
Jingjing Zhu, Jing Zhang, Ping Wang, Xiuying Liu, Jingjing Liu, Yichao Feng, Mary Yue Jiang, Zhiqiao Feng, Xiaoqing Yao, Jianxun Wang   +9 more
doaj   +2 more sources

Therapeutic efficacy and safety of Xuebijing in traumatic brain injury: systematic review and meta-analysis [PDF]

Frontiers in Pharmacology
BackgroundTraumatic brain injury (TBI) represents a major global health challenge. Several clinical studies have suggested that Xuebijing (XBJ)—a patented Chinese botanical drug preparation may confer neuroprotective and anti-inflammatory benefits in TBI.
Yihan Sun, Jiaqi Li, Xinyue Cui, Meiyu Yu, Boying Xiao, Junyuan Lv, Ziqi Li, Zhijing Wei, Niaoyao He, Zhuoyu Li, Hao Wen   +10 more
doaj   +2 more sources

Antiseptic Activity of Ethnomedicinal Xuebijing Revealed by the Metabolomics Analysis Using UHPLC-Q-Orbitrap HRMS

Frontiers in Pharmacology, 2018
Xuebijing (XBJ) injection is an ethnomedicinal formula that has been widely used in the therapy of sepsis in China. However, the underlying theraputic mechanisms remain uninvestigated. In this research, a metabolomic method based on UHPLC-Q-Orbitrap HRMS
Lihua Zuo, Lihua Zuo, Lin Zhou, Lin Zhou, Tanye Xu, Tanye Xu, Zhuolun Li, Zhuolun Li, Liwei Liu, Liwei Liu, Yingying Shi, Yingying Shi, Jian Kang, Jian Kang, Guanmin Gao, Shuzhang Du, Shuzhang Du, Zhi Sun, Zhi Sun, Xiaojian Zhang, Xiaojian Zhang   +20 more
doaj   +2 more sources

Examining the effector mechanisms of Xuebijing injection on COVID-19 based on network pharmacology [PDF]

BioData Mining, 2020
Background Chinese medicine Xuebijing (XBJ) has proven to be effective in the treatment of mild coronavirus disease 2019 (COVID-19) cases. But the bioactive compounds and potential mechanisms of XBJ for COVID-19 prevention and treatment are unclear. This
Wen-jiang Zheng, Qian Yan, Yong-shi Ni, Shao-feng Zhan, Liu-liu Yang, Hong-fa Zhuang, Xiao-hong Liu, Yong Jiang   +7 more
doaj   +3 more sources

Scientific Evidence of Xuebijing Injection in the Treatment of Sepsis [PDF]

Evidence-Based Complementary and Alternative Medicine, 2021
Objectives. To systematically collate, appraise, and synthesize the current evidence on the Xuebijing injection (XBJI) for sepsis. Methods. Eight databases were searched for systematic reviews (SRs) or meta-analyses (MAs) on XBJI for sepsis. Assessing the Methodological Quality of Systematic Reviews-2 (AMSTAR-2), Preferred Reporting Item for Systematic
Sa Tian, Defang Qin, Yixuan Ye, Huawei Yang, Shuguang Chen, Tao Liu, Luming Hu, Huiming Li, Qian Niu, Xingzhan Zhang   +9 more
openaire   +2 more sources

Weaker Response to XueBiJing Treatment in Severe Community-Acquired Pneumonia Patients With Higher Body Mass Index or Hyperglycemia: A Post Hoc Analysis of a Randomized Controlled Trial

Frontiers in Pharmacology, 2022
Background: Overweight and hyperglycemia might result in poor prognosis in patients with severe community-acquired pneumonia (SCAP). XueBiJing treatment could significantly improve the outcomes of patients with SCAP.
Yansha Song, Xiaocen Wang, Cuicui Chen, Tingting Wei, Ke Lang, Dong Yang, Yuanlin Song   +6 more
doaj   +1 more source

Comparative Efficacy of Seven Kinds of Chinese Medicine Injections in Acute Lung Injury and Acute Respiratory Distress Syndrome: A Network Meta-analysis of Randomized Controlled Trials

Frontiers in Pharmacology, 2021
Background: Chinese medicine injection is wildly used in Acute Lung Injury and Acute respiratory distress syndrome (ALI/ARDS) treatment. However, what kinds of CMIs are more effective in the ALI/ARDS treatment is uncertain.Objectives: Compare the ...
Jie Guo, Jie Guo, Jia Zhu, Qian Wang, Juan Wang, Juan Wang, Yaodan Jia   +6 more
doaj   +1 more source

Exploring the Protective Mechanism of Xuebijing Injection Against Sepsis. [PDF]

J Inflamm Res
Zhouguang Jiao,1,* Haikuan Yu,2,* Xuekong Li,3 Xiaoqing Chen,4 Fangfang Jiao,3 Taojin Feng,5 Dewen Kong,2 Rongxian Jiang,2 Jingguang Jin,6 Yulong Song,7 Xinhua Luo6 1College of Basic Medical Science, Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-Autoimmune Disease of Hebei Province, State Key Laboratory of New ...
Jiao Z, Yu H, Li X, Chen X, Jiao F, Feng T, Kong D, Jiang R, Jin J, Song Y, Luo X.   +10 more
europepmc   +3 more sources

A Five-Dimensional Network Meta-Analysis of Chinese Herbal Injections for Treating Acute Tonsillitis Combined With Western Medicine

Frontiers in Pharmacology, 2022
Background: Acute tonsillitis has high morbidity. Chinese herbal injections (CHIs) were reported to be useful in treating acute tonsillitis and might reduce the probability of antibiotic resistance.
Peiying Huang, Peiying Huang, Yin Li, Bixuan Huang, Shuai Zhao, Shuai Zhao, Li Chen, Li Chen, Hansu Guan, Yan Chen, Yuchao Feng, Yuchao Feng, Xiaoyan Huang, Xiaoyan Huang, Yi Deng, Yi Deng, Sisi Lei, Sisi Lei, Qihua Wu, Qihua Wu, Haobo Zhang, Haobo Zhang, Zhongyi Zeng, Linsheng Zeng, Bojun Chen, Bojun Chen, Bojun Chen   +26 more
doaj   +1 more source