Results 61 to 70 of about 193 (86)

Xuebijing Improves Intestinal Microcirculation Dysfunction In Septic Rats By Regulating The Vegf-A/Pi3K/Akt Signaling Pathway [PDF]

BACKGROUND: This study aims to explore whether Xuebijing (XBJ) can improve intestinal microcirculation dysfunction in sepsis and its mechanism. METHODS: A rat model of sepsis was established by cecal ligation and puncture (CLP).
Tang, A-Ling, Liu, Xiao-Yu, Sun, Li-Chao, Zhang, Guo-Qiang, Li, Yan, Gao, Nan, Yan, Sheng-Tao   +6 more
core   +1 more source

Heat stress-induced disruption of endothelial barrier function is via PAR1 signaling and suppressed by Xuebijing injection. [PDF]

, 2015
Increased vascular permeability leading to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) is central to the pathogenesis of heatstroke.
Zhenglian Wang (693435), Xiaohua Guo (693436), Yanan Liu, Qiulin Xu, Gengbiao Zhou, Gengbiao Zhou (693437), Qiaobing Huang, Jingxian Liu, Xiaohua Guo, Jingxian Liu (257255), Yanan Liu (114059), Zhenglian Wang, Qiulin Xu (693434), Lei Su (361548), Lei Su, Qiaobing Huang (529646)   +15 more
core   +1 more source

Xuebijing enhances antitumor efficacy of anti-CD19 CAR-T cells

Objective: To investigate the effects and mechanisms of Xuebijing injection (XBJ) on Chimeric antigen receptor-T (CAR-T) cell function and its therapeutic potential against CAR-T therapy-associated cytokine storms (CRS).
Zhiqiao Feng, Jingjing Liu, Xiuying Liu, Xiaoqing Yao, Jianxun Wang, Yichao Feng, Mary Yue Jiang, Jing Zhang, Ping Wang, Jingjing Zhu   +9 more
core   +1 more source

Baseline characteristics.

, 2015
Note: XBJ, Xuebijing injection; BMI, Body mass index; APACHE II, Acute Physiology and Chronic Health Evaluation II; NS, no significance.Baseline characteristics.
Ping Gong (37151), Zhidan Lu (732011), Na Wang (193263), Jing Xing (342644), Yu Zhang (12946)   +4 more
core   +1 more source

28-day survival rates of patients ingesting different volumes of 20% liquid paraquat (w/v).

, 2015
Note: XBJ, Xuebijing injection.28-day survival rates of patients ingesting different volumes of 20% liquid paraquat (w/v).
Ping Gong (37151), Zhidan Lu (732011), Na Wang (193263), Jing Xing (342644), Yu Zhang (12946)   +4 more
core   +1 more source

Identifying Baicalein as a Key Bioactive Compound in XueBiJing Targeting KEAP1: Implications for Antioxidant Effects

Background: XueBiJing injection (XBJ) is renowned for its multi-target pharmacological effects, including immunomodulatory, antithrombotic, and antioxidant activities, offering potential therapeutic benefits for patients with severe infections such as ...
Shang-Fu Li, Hsi-Yuan Huang, Yi-Gang Chen, Jie Ni, Hua-Li Zuo, Li-Ping Li, Ji-Han Xiao, Ting-Syuan Lin, Jia-Tong Xu, Hsien-Da Huang, Xiao-Xuan Cai, Jing Li, Yi-Bing Wang, Zi-Hao Zhu, Kun-Meng Liu, Yang-Chi-Dung Lin, Ji-Hang Chen, Yuan-Jia Hu   +17 more
core   +1 more source

Revealing the molecular mechanisms underlying Xuebijing against sepsis and septic acute kidney injury via bioinformatics and experimental approaches [PDF]

BackgroundSepsis and its related complication acute kidney injury (septic-AKI) are associated with high mortality and morbidity, and have become a global health challenge.
Juan Tang, Tchivelekete, Gabriel Mbuta, Wang, Le, Yi Guo, Shu, Xinhua, Baran, Michal R., Michal R Baran, Gabriel Mbuta Tchivelekete, Xinhua Shu, Kaiqi Ren, Li, Xing, Le Wang, Tang, Juan, Guo, Yi, Bai, Yang, Xing Li, Yang Bai, Ren, Kaiqi, Yan, Weijian, Weijian Yan   +19 more
core   +1 more source

Xuebijing alleviates acute hydrogen sulfide-induced pyroptosis in rat spleen via suppression of the caspase-1/NLRP3 pathway

Hydrogen sulfide (H 2 S) is a pervasive environmental toxicant with well-established immunotoxic effects.
Yuhao Han, Yonggang Ma, Hongyan Zhao, Hui Zou, Yan Chen, Lulu Ding, Xishuai Tong, Ruilong Song, Zongping Liu   +8 more
core   +1 more source

Xuebijing improves inflammation and pyroptosis of acute lung injury by upregulating miR-181d-5p-mediated SPP1 inactivation

Background: Xuebijing (XBJ) is widely applied in the treatment of Acute Lung Injury (ALI). This study focused on the potential mechanism of XBJ in Lipopolysaccharide (LPS)-induced ALI. Methods: The rat ALI model was established by injection of LPS (10 mg/
Wu, XiaoYong, Xin, RuoMei, Yang, ChengRui, Sun, FangYuan, Wang, YanLiang, Zhang, YanZhong, Zheng, FengXian   +6 more
core  

Beneficial effect of Xuebijing against Pseudomonas aeruginosa infection in Caenorhabditis elegans

Frontiers in Pharmacology, 2022
Haibo Qiu, Songqiao Liu, Dayong Wang
exaly