Results 181 to 190 of about 167,087,863 (243)

ACP5‐positive macrophages contribute to cerebral oedema and neuroinflammation after traumatic brain injury

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Integrated transcriptomic analyses identified an ACP5‐positive monocyte/macrophage population enriched in the injured brain within 1–3 days after traumatic brain injury (TBI). Pharmacological and genetic targeting of ACP5 attenuated cerebral oedema and neuroinflammation, preserved blood–brain barrier integrity, and improved long‐term cognitive outcomes.
Dang Hanhan, He Kun, Zhang Yulian, Zhang Chuanpeng, Zhang Yunsheng, Wang Zixi, Yang Xu, Chen Pengyu, Zhang Li, Yu Yanbing   +9 more
wiley   +1 more source

Molecular Diagnosis of 46,XY Disorders of Sex Development: An Efficient Initial Molecular Analysis Using a Custom-Designed Targeted Gene Panel in a Single-Center Study.

Sex Dev
Poyrazoglu S, Aghayev A, Toksoy G, Karaman B, Aslanger AD, Avci S, Altunoglu U, Karaman V, Yildiz M, Abali ZY, Bas F, Basaran S, Darendeliler F, Uyguner ZO.   +13 more
europepmc   +1 more source

Submicroscopic copy-number variations associated with 46,XY disorders of sex development. [PDF]

Mol Cell Pediatr, 2015
Kon M, Fukami M.
europepmc   +1 more source

Low Preoperative Free Triiodothyronine, Particularly in Females, Is Associated With Reduced Weight Loss and Diabetes Remission After Bariatric Surgery in Euthyroid Adults

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Aims With the rising prominence of GLP‐1 receptor agonists, identifying predictors of optimal bariatric surgery candidates has become increasingly important. We investigated cross‐sectional relationships between thyroid hormones and obesity‐related parameters, and evaluated the predictive value of baseline thyroid hormones for weight loss (WL)
Shaobo Li, Yinfang Tu, Hongwei Zhang, Yunfeng Xiao, Yuqian Bao, Jun Yin, Yujin Ma, Haoyong Yu, Fengjing Liu   +8 more
wiley   +1 more source

Reproducibility of Serum Androgen Concentrations by Liquid Chromatography Mass Spectrometry in Healthy Male and Female Athletes

Drug Testing and Analysis, Volume 18, Issue 9, Page 1220-1224, September 2026.
Box and whiskers plots show the distributions of serum testosterone (T), dihydrotestosterone (DHT), androstenedione (A4), and the ratios of T/FDHT and T/A4. ABSTRACT Detection of androgen doping relies on mass spectrometry‐based methods to detect natural endogenous and exogenous androgens in urine and serum. To distinguish exogenous administration from
D. J. Handelsman, S. Bermon
wiley   +1 more source

High incidence of Y‐chromosome mosaicism in male and female individuals with mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy

Epilepsia, Volume 67, Issue 9, Page 4907-4921, September 2026.
Abstract Objective Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is an underrecognized pediatric cortical lesion associated with somatic X‐linked SLC35A2 variants in approximately 50% of individuals. The genetic etiology in individuals without detectable SLC35A2 mutations remains undefined, which limits
Erica Cecchini, Till Hartlieb, Ahmed Gaballa, Katja Kobow, Mitali Katoch, Paraskevi Chasani, Georgia Vasileiou, Wiebke Hofer, Lea M. Reisch, Manfred Kudernatsch, Christian G. Bien, Roland Coras, Ingmar Blümcke, Lucas Hoffmann   +13 more
wiley   +1 more source

Structural Characteristics and Immunoregulatory Effects of Colla Corii Asini Peptides with Iron‐Chelating Capacity

Food Frontiers, Volume 7, Issue 5, September 2026.
Ejiao peptides were fractionated to iron‐chelating F2 (enriched in E‐Xn‐P motif), which restored immune function in CTX‐induced immunosuppressed mice via synergistic regulation of immunity and iron homeostasis. ABSTRACT Iron homeostasis is closely related to immune function, yet the structural basis of food‐derived peptides that modulate this iron ...
Qing‐Tao Zhan, Zi‐Wei Zhao, Jian‐Hang Cai, Xue‐Mei Ge, Shuang‐Di Chen, Xue Tang, Xue‐Ying Ma, Liu‐Ping Fan, Issoufou Amadou, Xiang‐Rong Cheng   +9 more
wiley   +1 more source

Structural Characterization and UVB Irradiation Protective Effect of the Polysaccharide From Tremella fuciformis After Microbial Fermentation

Food Frontiers, Volume 7, Issue 5, September 2026.
ABSTRACT Tremella fuciformis is an edible mushroom rich in bioactive polysaccharides. In this study, T. fuciformis was extracted by citric acid under high temperature and high‐pressure (121°C, 0.1 MPa), followed by fermentation with Saccharomyces cerevisiae CH006 and Thermus thermophilus HB27.
Xin‐Yan He, Jun‐Qiao Wang, Yi‐Qi Lin, Sih‐Yu Chu, Wen‐Xin Wang, Xuan‐Han Xiao, Yu‐Ke Hou, Xiao‐Feng Qiu, Shao‐Ping Nie, Zhi‐Jiang Wang, Huan‐Yu Liu   +10 more
wiley   +1 more source

Prenatal Stress Induced by Maternal Immune Activation Disrupts GABAergic Inhibition and Mossy Fiber Plasticity in the Rat Dentate Gyrus‐CA3 Circuit

Hippocampus, Volume 36, Issue 5, September 2026.
ABSTRACT Viral infections during critical periods of pregnancy trigger inflammatory responses that alter offspring brain development and behavior, resulting in psychiatric disorder‐associated phenotypes. This condition is commonly referred to as prenatal stress induced by maternal immune activation (MIA).
Johaly Anguiano‐Buenfil, Isabel Sollozo‐Dupont, Luis A. Márquez, Angelica Zepeda, Emilio J. Galván   +4 more
wiley   +1 more source