ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan +5 more
wiley +1 more source
FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model
FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble +9 more
wiley +1 more source
Health risk and toxicity assessment of exhaust air from non-incineration devices for hospital waste treatment in Tehran, Iran. [PDF]
Bahmani Z +3 more
europepmc +1 more source
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng +14 more
wiley +1 more source
Use of the TIPS Technique as a Possible Method of Acute Inhalation Toxicity Assessment. [PDF]
Saleh DM +8 more
europepmc +1 more source
All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao +8 more
wiley +1 more source
Understanding Non-isothermal Crystallization Behaviors of Polyethylene-Derived Vitrimers. [PDF]
Valdez S, Qiang Z.
europepmc +1 more source
Mixed‐Polymer Hole Transport Layers Reinforce Au‐Anode Top Emitting Perovskite Light Emitting Diodes
Au‐anode corrosion is shown to occur rapidly under voltage bias in MAPbI3 perovskite LEDs. Resulting Au+ migration quickly leads to device shorting and unstable emission during constant current driving. We demonstrate that using a simple mixed‐polymer hole transport layer containing polyTPD and PVK can reduce Au‐corrosion and stabilize LED operation ...
James C. Loy +5 more
wiley +1 more source
Pathways to Aromatics in the Catalytic Pyrolysis of a Polyvinylchloride Model Compound Revealed by Operando Photoelectron Photoion Coincidence Spectroscopy. [PDF]
Cabana J +16 more
europepmc +1 more source
Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami +15 more
wiley +1 more source

