Results 41 to 50 of about 11,512 (298)

An open-path, hand-held laser system for the detection of methane gas [PDF]

, 2005
We have developed an open-path hand-held gas detector incorporating a distributed feedback InGaAs laser diode at 1.65 µm. Incorporated into a hand-held transceiver unit, the emitted laser beam is backscattered from nearby surfaces, collected and focused ...
Padgett, M, Murray, S, van Well, Ben, Gibson, G, Strzoda, Rainer, Padgett, Miles, van Well, B, Hodgkinson, Jane, Pride, Russ D., Murray, Stuart, Gibson, Graham, Strzoda, R, Pride, R, Hodgkinson, J   +13 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Sub-ppb Level Detection of BTEX Gaseous Mixtures with a Compact Prototype GC Equipped with a Preconcentration Unit

Micromachines, 2019
In this work, a compact gas chromatograph prototype for near real-time benzene, toluene, ethylbenzene and xylenes (BTEX) detection at sub-ppb levels has been developed. The system is composed of an aluminium preconcentrator (PC) filled with Basolite C300,
Irene Lara-lbeas, Alberto Rodríguez-Cuevas, Christina Andrikopoulou, Vincent Person, Lucien Baldas, Stéphane Colin, Stéphane Le Calvé   +6 more
doaj   +1 more source

Substrate-restricted methanogenesis and limited volatile organic compound degradation in highly diverse and heterogeneous municipal landfill microbial communities

ISME Communications, 2022
Microbial communities in landfills transform waste and generate methane in an environment unique from other built and natural environments. Landfill microbial diversity has predominantly been observed at the phylum level, without examining the extent of ...
Alexandra H. Sauk, Laura A. Hug
doaj   +1 more source

Ecotoxicological profile of xylenes : working party on ecotoxicological profiles of chemicals

, 1986
The xylenes (o, m, p), which are produced in large amounts and widely used, must be considered as environmental contaminants, as they have been identified in the atmosphere of many countries.
Di Domenico A., Marinovich M., Galli E., Galli C. L., Jori A., Calamari D., Silano V.   +6 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Unmasking the aromatic production Industry's VOCs: Unraveling environmental and health impacts

Atmospheric Environment: X
In this study, we conducted a thorough investigation into the critical volatile organic compounds (VOCs), namely benzene, toluene, and xylenes (BTX), originating from the aromatic production industry.
Jutarat Keawboonchu, Sarawut Thepanondh, Vanitchaya Kultan, Nattaporn Pinthong, Wissawa Malakan, Shinya Echigo, Suchon Chatphanchan   +6 more
doaj   +1 more source

Generation and Cycloaddition of o-Quinodimethane in Aqueous Medium

Molecules, 2001
o-Quinodimethane can be generated from =α,α'-dihalo-o-xylenes using zinc in aqueous solution. In the presence of activated dienophiles cycloadducts can be obtained directly.
Margarete F. da Silva, Lothar W. Bieber
doaj   +1 more source