Results 61 to 70 of about 9,070 (259)
Economics is the engine that drives industry. For complete understanding of project economics four major items must be discussed; capital requirements, operating expenses, cash flow and profitability measures.
H.R. Omran +3 more
doaj +1 more source
Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla +15 more
wiley +1 more source
Deterministic Integration of Quantum Emitters and Optical Cavities in a Van Der Waals Crystal
The work demonstrates fabrication of Circular Bragg Grating (CBG) cavities with embedded emitters in hBN. The cavities are fabricated around a pre‐characterised quantum emitter. The integrated platform enables light matter interaction and access to brighter emitters and spins in hBN.
James Liddle‐Wesolowski +8 more
wiley +1 more source
Based on density measurements, partial and excess molar volumes for binary mixtures of nitrobenzene and benzaldehyde with three isomers of xylene have been measured. The whole range of composition and temperatures from T = (298.15 to 318.15) K at ambient
Hamid R. Rafiee, Farshid Frouzesh
doaj +1 more source
In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu +7 more
wiley +1 more source
The constituents of gasoline: benzene, toluene, ethylbenzene and xylenes (BTEX) are frequently found in soils due to leaks in fuel storage tanks and they present chronic toxicity. In this work it was developed and validated a methodology of BTEX analysis
Jurandir Pereira Pinto +3 more
doaj
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang +19 more
wiley +1 more source
RESUMEN Antecedentes: En anatomía patológica, existen variedad de agentes químicos que deben ser controlados. Por su potencial cancerígeno destacan el Formaldehído (CH2O), Xileno y los Compuestos Orgánicos Volátiles (COVs).
Mileida Andreina Peñalver Paolini +2 more
doaj
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang +12 more
wiley +1 more source
In this study the efficiency of advanced oxidative processes (AOPs) were investigated toward the degradation of aqueous solutions containing benzene, toluene and xylenes (BTX).
Elaine Regina Lopes Tiburtius +3 more
doaj +1 more source

