Results 151 to 160 of about 22,741,673 (262)

Mosaic Loss of Y Chromosome and Risks of Peripheral Arterial and Aortic Diseases. [PDF]

JACC Adv
Zeng Z, Li Y, Li Z, Liu H, Chen B, Wang H, Meng Q, Chen R, Jin L, Yu C, Wang X, Chen J, Li X, Zheng Z.   +13 more
europepmc   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Correction: How convincing is a matching Y-chromosome profile? [PDF]

PLoS Genet
Andersen MM, Balding DJ.
europepmc   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Overcoming Artificial Structures in Resolution‐Enhanced Hi‐C Data by Signal Decomposition and Multi‐Scale Attention

Advanced Science, EarlyView.
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li, Kelly Yichen Li, Chiara Nicoletti, Stephen Kwok‐Wing Tsui, Pier Lorenzo Puri, Qin Cao, Kevin Y. Yip   +6 more
wiley   +1 more source

Chromosome-level reference genome assembly of O. loti

We present a high-quality chromosome-level genome of O. loti, which was obtained using a combination of ONT long-read sequencing, Illumina short-read sequencing and chromosome conformation capture (Hi-C) technologies.
Yingning Luo (17671371)
core   +1 more source

The Genetic Structure of the Romanian Male Population Revealed by 27 Y-Chromosome STR Loci. [PDF]

Int J Mol Sci
Popoiu G, Stanciu F, Popescu P, Cuțăr V, Vladu S, Nicola V, Procopciuc A, Rădulescu A, Cotolea A, Georgescu SE.   +9 more
europepmc   +1 more source

Primary Tumor-Associated Loss of the Y Chromosome and Clinical Outcome in Metastatic Colorectal Cancer. [PDF]

Genes Chromosomes Cancer
Isnard A, Decraecker M, Fernandez B, Smith D, Dubus P, Dabernat S, Mansier O, Amintas S.   +7 more
europepmc   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Human Y chromosome pan-organ mapping reveals progressive mosaic loss from normal to cancer. [PDF]

JCI Insight
Gertych A, Ye H, Chen X, Vail E, Ramanujan VK, Brady L, True LD, Nelson PS, Carroll PR, Theodorescu D.   +9 more
europepmc   +1 more source