Results 141 to 150 of about 2,765,658 (238)

A network-based EEG source imaging framework for noninvasive localization of epileptogenic zones in MRI-negative focal drug-resistant epilepsy. [PDF]

BMC Neurol
Huang S, Hu X, Wang Y, Gao W, Fang Q.
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Scaling deep learning for material imaging with a pseudo 3D model for domain transfer. [PDF]

Nat Commun
Tang K, Armstrong RT, Mostaghimi P, Niu Y, Meyer Q, Zhao C, Finegan DP, Popeil M, Singh K, Menke H, Dimou AP, Bultreys T, Mascini A, Knackstedt M, Da Wang Y.   +14 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Thermal light with enhanced oscillating bunching in field-tested photon-counting LIDAR. [PDF]

Nat Commun
Staffas T, Cleveborg J, Gao J, Elshaari AW, Zwiller V.   +4 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

CDFFusion: A Color-Deviation-Free Fusion Network for Nighttime Infrared and Visible Images. [PDF]

Sensors (Basel)
Chen H, Zhang T, Zhai S, Tong X, Zhu R.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Pangenome dynamics and population structure of the zoonotic pathogen Salmonella enterica serotype Hadar. [PDF]

Nat Commun
Tagg KA, Peñil-Celis A, Webb HE, Stapleton GS, Ellison Z, Leeper M, Kim JY, Simmons M, Tillman G, Li C, Harris B, Morningstar-Shaw BR, Steele MK, Mallal D, Matzinger S, Manion K, Hergert J, Wagner JM, Schwensohn C, Brandenburg JM, Shaw S, Benedict K, Folster JP, Dessai U, Redondo-Salvo S, Garcillan-Barcia MP, de la Cruz F.   +26 more
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source