Results 1 to 10 of about 10,690,340 (404)
Natural selection reduced diversity on human Y chromosomes [PDF]
arXiv, 2013 The human Y chromosome exhibits surprisingly low levels of genetic diversity. This could result from neutral processes if the effective population size of males is reduced relative to females due to a higher variance in the number of offspring from males than from females.
Lohmueller, Kirk E. +2 more
arxiv +12 more sources
Massive gene amplification on a recently formed Drosophila Y-chromosome [PDF]
Nature Ecology & Evolution, 2018 Widespread loss of genes on the Y is considered a hallmark of sex chromosome differentiation. Here we show that the initial stages of Y evolution are driven by massive amplification of distinct classes of genes. The neo-Y chromosome of Drosophila miranda
D. Bachtrog +2 more
semanticscholar +3 more sources
Forensic use of Y-chromosome DNA: a general overview [PDF]
Human Genetics, 2017 The male-specific part of the human Y chromosome is widely used in forensic DNA analysis, particularly in cases where standard autosomal DNA profiling is not informative.
M. Kayser
semanticscholar +5 more sources
Complex genomic rearrangements of the Y chromosome in a premature infant [PDF]
Molecular CytogeneticsBackground Chromoanagenesis is an umbrella term used to describe catastrophic “all at once” cellular events leading to the chaotic reconstruction of chromosomes. It is characterized by numerous rearrangements involving a small number of chromosomes/loci,
Stephanie A. Balow +6 more
doaj +2 more sources
Chromosomal aneuploidies and associated rare genetic syndromes involved in male infertility [PDF]
Journal of Men's Health, 2021 Background and objectives: Recent investigations have reported more than 70 genetic syndromes involved in male infertility; however, the majority of these syndromes are extremely rare.
Eisa Tahmasbpour Marzouni +2 more
doaj +1 more source
Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality
Science, 2022 Hematopoietic mosaic loss of Y chromosome (mLOY) is associated with increased risk of mortality and age-related diseases in men, but the causal and mechanistic relationships have yet to be established. Here, we show that male mice reconstituted with bone
S. Sano +24 more
semanticscholar +1 more source
Genome Biology, 2021 The origin of sex chromosomes requires the establishment of recombination suppression between the proto-sex chromosomes. In many fish species, the sex chromosome pair is homomorphic with a recent origin, providing species for studying how and why ...
Lingzhan Xue +8 more
semanticscholar +1 more source
Balkan Journal of Medical Genetics, 2022 A case study of a 4 year old child with hypospadias and cryptorchidism on the right side is presented. Combined analysis by Karyotype and FISH showed a mosaic pattern of 48, XYYY (73%); 47,XYY (7%); 46,XY (7%) and 45,X (13%).
Sabnis AS, Bhusare D
doaj +1 more source
Multiplex-Polymerase Chain Reaction for Detecting Microdeletions in The Azoospermia Factor Region of Y Chromosome in Iranian Couples with Non-Obstructive Infertility and Recurrent Pregnancy Loss [PDF]
International Journal of Fertility and Sterility, 2018 Background Approximately 15% of couples are infertile with the male factor explaining approximately 50% of the cases. One of the main genetic factors playing a role in male infertility is Y chromosomal microdeletions within the proximal long arm of the Y
Afsaneh Mojtabanezhad Shariatpanahi +4 more
doaj +1 more source
Recognition of the Y chromosome in Turner syndrome using peripheral blood or oral mucosa tissue [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2021 Purpose Turner syndrome is defined as total or partial loss of the second sex chromosome in a phenotypically female patient. Due to the possibility of hidden mosaicism of fragments of the Y chromosome and development of gonadoblastoma, we evaluated the ...
Lene Garcia Barbosa +3 more
doaj +1 more source