Results 91 to 100 of about 10,690,340 (404)
FEBS Letters, EarlyView.Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel +2 more
wiley +1 more source
Review of the Y chromosome and hypertension
Brazilian Journal of Medical and Biological Research, 2000 The Y chromosome from spontaneously hypertensive rats (SHR) has a locus that raises blood pressure 20-25 mmHg. Associated with the SHR Y chromosome effect is a 4-week earlier pubertal rise of testosterone and dependence upon the androgen receptor for the full blood pressure effect.
Ely, D., Turner, M., Milsted, A.
openaire +6 more sources
Male Infertility and the Y Chromosome [PDF]
The American Journal of Human Genetics, 1999 Although it has been established since the 1970s thatdeletions of the long arm of the Y chromosome are as-sociated with spermatogenic failure, only in the last fewyears have these regions been described at the molecularlevel. In parallel, Y-linked genes and gene families thatmay explain the phenotypes of men carrying these de-letions have been ...
Csilla Krausz +2 more
openaire +3 more sources
Repetitive DNA Sequences in the Human Y Chromosome and Male Infertility
Frontiers in Cell and Developmental Biology, 2022 The male-specific Y chromosome, which is well known for its diverse and complex repetitive sequences, has different sizes, genome structures, contents and evolutionary trajectories from other chromosomes and is of great significance for testis ...
Yong Xu, Qianqian Pang
doaj +1 more source
Y Chromosome of Aisin Gioro, the Imperial House of Qing Dynasty [PDF]
Journal of Human Genetics, (2 April 2015), 2014 House of Aisin Gioro is the imperial family of the last dynasty in Chinese history - Qing Dynasty (1644 - 1911). Aisin Gioro family originated from Jurchen tribes and developed the Manchu people before they conquered China. By investigating the Y chromosomal short tandem repeats (STRs) of 7 modern male individuals who claim belonging to Aisin Gioro ...
arxiv +1 more source
The Drosophila Y Chromosome Affects Heterochromatin Integrity Genome-Wide
bioRxiv, 2017 The Drosophila Y-chromosome is gene poor and mainly consists of silenced, repetitive DNA. Nonetheless, the Y influences expression of hundreds of genes genome-wide, possibly by sequestering key components of the heterochromatin machinery away from other ...
E. J. Brown +2 more
semanticscholar +1 more source
Hexavalents in spermatocytes of Robertsonian heterozygotes between Mus m. domesticus 2n 26 from the Vulcano and Lipari Islands (Aeolian Archipelago, Italy) [PDF]
, 2018 The size and shape of the chromosomes, as well as the chromosomal domains that compose them, are determinants in the distribution and interaction between the bivalents within the nucleus of spermatocytes in prophase I of meiosis.
Eliana Ayarza +6 more
core +3 more sources
FEBS Letters, EarlyView.To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche +2 more
wiley +1 more source
The Y chromosome and the heartache of males [PDF]
Investigative Genetics, 2012 It is well established that atherosclerotic coronary heartdisease (CHD) presents sexual dimorphism in its inci-dence, age of onset, progression, treatment, morbidityand mortality. Men are more commonly affected and diemore often and younger from CHD compared with theirage-matched partners.
openaire +3 more sources
Automated clinical system for chromosome analysis [PDF]
, 1978 An automatic chromosome analysis system is provided wherein a suitably prepared slide with chromosome spreads thereon is placed on the stage of an automated microscope.
Castleman, K. R. +4 more
core +1 more source