Results 91 to 100 of about 858,060 (289)
Analysis of Y Chromosome Microdeletion in Indonesian Males
Makara Journal of Health Research, 2010 The aim of this study is to find out Y chromosome microdeletion in Indonesian azoospermic men. This study used the PCR method with five STS to locate deletion on three different subregions (AZFa, AZFb, and AZFc) of azoospermic men and one STS to amplify ...
Dwi Anita Suryandari +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Self-assembly and DNA binding of the blocking factor in X chromosome inactivation [PDF]
, 2007 X chromosome inactivation (XCI) is the phenomenon occurring in female mammals whereby dosage compensation of X-linked genes is obtained by transcriptional silencing of one of their two X chromosomes, randomly chosen during early embryo development. The
Antonella Prisco +2 more
core +3 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Y chromosome haplogroups in the Bosnian-Herzegovinian population based on 23 Y-STR loci [PDF]
, 2017 In a study of the Bosnian-Herzegovinian (B&H) population, Y chromosome marker frequencies for 100 individuals, generated using PowerPlex® Y23 kit, were used to perform Y chromosome haplogroup assignment via Whit Athey’s Haplogroup Predictor.
Ašić, Adna +4 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Comparison of genetic and linguistic data as an approach to studying human migrations
Учёные записки Казанского университета: Серия Естественные науки, 2018 The origin of humans and their settling around the globe are explored using various scientific methods. Genomic profiling data increasing in volume every day are of particular interest to researchers of these problems.
E.A. Boulygina +2 more
doaj
Y Chromosome Microsatellites Variation in Bali Cattle (Bos Sondaicus) Population [PDF]
, 2009 Seven Y chromosome specific microsatellites were typed in a sample of 36 unrelated males from Bali cattle breed. Analysis variation of microsatellites marker in Bali cattle were determinate from PCR products by using 7 primer pairs that flanking ...
Gurnadi, R. (RE) +3 more
core
How Do Y-Chromosomes Modulate Genome-Wide Epigenetic States: Genome Folding, Chromatin Sinks, and Gene Expression [PDF]
, 2014 The Y chromosomes of Drosophila melanogaster and D. simulans contain only a handful of protein-coding genes, which are related to sperm mobility and reproductive fitness.
Francisco, Flávio O., Lemos, Bernardo
core +1 more source