Results 141 to 150 of about 10,690,340 (404)
The Challenges of Chromosome Y Analysis and the Implications for Chronic Kidney Disease
Frontiers in Genetics, 2019 The role of chromosome Y in chronic kidney disease (CKD) remains unknown, as chromosome Y is typically excluded from genetic analysis in CKD. The complex, sex-specific presentation of CKD could be influenced by chromosome Y genetic variation, but there ...
Kerry Anderson +5 more
doaj +1 more source
A Quantitative Understanding of Human Sex Chromosomal Genes [PDF]
arXiv, 2012 In the last few decades, the human allosomes are engrossed in an intensive attention among researchers. The allosomes are now already been sequenced and found there are about 2000 and 78 genes in human X and Y chromosomes respectively. The hemizygosity of the human X chromosome in males exposes recessive disease alleles, and this phenomenon has ...
arxiv
Genome-Wide Gene Expression Effects of Sex Chromosome Imprinting in Drosophila [PDF]
, 2014 Imprinting is well-documented in both plant and animal species. In Drosophila, the Y chromosome is differently modified when transmitted through the male and female germlines.
Branco, Alan T. +4 more
core +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Convergence of Y chromosome STR haplotypes from different SNP haplogroups compromises accuracy of haplogroup prediction [PDF]
arXiv, 2013 Short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) are two kinds of commonly used markers in Y chromosome studies of forensic and population genetics. There has been increasing interest in the cost saving strategy by using the STR haplotypes to predict SNP haplogroups.
arxiv
A Comparison of the Trojan Y Chromosome Strategy to Harvesting Models for Eradication of Non-Native Species [PDF]
, 2018 The Trojan Y Chromosome Strategy (TYC) is a promising eradication method for biological control of non-native species. The strategy works by manipulating the sex ratio of a population through the introduction of \textit{supermales} that guarantee male offspring. In the current manuscript, we compare the TYC method with a pure harvesting strategy.
arxiv +1 more source
Phenotypic pattern over centric fusion clinal variation in the water-hyacinth grasshopper, Cornops aquaticum (Orthoptera: Acrididae) [PDF]
, 2018 The water-hyacinth grasshopper, Cornops aquaticum, occurs in freshwater environments in the New World between latitudes 23°N and 35°S. At the southernmost margin of this distribution the populations are polymorphic for three centric fusions (Robertsonian
Bownes +21 more
core +1 more source
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
Sex chromosome-to-autosome transposition events counter Y-chromosome gene loss in mammals
Genome Biology, 2015 Although the mammalian X and Y chromosomes evolved from a single pair of autosomes, they are highly differentiated: the Y chromosome is dramatically smaller than the X and has lost most of its genes.
Jennifer F. Hughes +4 more
semanticscholar +1 more source
Y chromosome in turner syndrome : a case report [PDF]
, 2016 In man, the Y chromosome spans approximately 58 million base pairs and represents just 1% of the total DNA in a male cell.1 Sex is determined in the SRY locus on the Y chromosome.
DeGiovanni, Joseph V. +3 more
core