Results 11 to 20 of about 10,446,015 (290)
Massive gene amplification on a recently formed Drosophila Y-chromosome [PDF]
Nature Ecology & Evolution, 2018 Widespread loss of genes on the Y is considered a hallmark of sex chromosome differentiation. Here we show that the initial stages of Y evolution are driven by massive amplification of distinct classes of genes. The neo-Y chromosome of Drosophila miranda
D. Bachtrog +2 more
semanticscholar +3 more sources
Y-Chromosome Microdeletions: A Review of Prevalence, Screening, and Clinical Considerations
The Application of Clinical Genetics, 2021 Matthew J Rabinowitz, Phillip J Huffman, Nora M Haney, Taylor P Kohn The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USACorrespondence: Taylor P KohnJames Buchanan Brady Urological Institute ...
Rabinowitz MJ +3 more
openalex +2 more sources
Chromosomal aneuploidies and associated rare genetic syndromes involved in male infertility [PDF]
Journal of Men's Health, 2021 Background and objectives: Recent investigations have reported more than 70 genetic syndromes involved in male infertility; however, the majority of these syndromes are extremely rare.
Eisa Tahmasbpour Marzouni +2 more
doaj +1 more source
Mosaic Turner Variant Adult Female Presenting with XO/XY Karyotype
Journal of Human Reproductive Sciences, 2023 Turner syndrome (TS) is the most frequently detected chromosomal abnormality in females caused by the partial or complete absence of second X chromosome.
Sigin George +3 more
doaj +1 more source
Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality
Science, 2022 Hematopoietic mosaic loss of Y chromosome (mLOY) is associated with increased risk of mortality and age-related diseases in men, but the causal and mechanistic relationships have yet to be established. Here, we show that male mice reconstituted with bone
S. Sano +24 more
semanticscholar +1 more source
Development and Forensic Application of EX20+30Y Kit
Fayixue Zazhi, 2021 ObjectiveTo develop a multiplex PCR amplification system （EX20+30Y for short） of 19 autosomes, 30 Y-STR loci plus the gender indicator, and evaluate its forensic application value.MethodsWith the six-color fluorescence labeling technology, a multiplex ...
ZHOU Xu-ming, GAO Deng-xing, LI Fa-yuan
doaj +1 more source
Genome Biology, 2021 The origin of sex chromosomes requires the establishment of recombination suppression between the proto-sex chromosomes. In many fish species, the sex chromosome pair is homomorphic with a recent origin, providing species for studying how and why ...
Lingzhan Xue +8 more
semanticscholar +1 more source
Frequency of Y chromosome Microdeletions in Turkish Infertile Men: Single Center Experience
Genel Tıp Dergisi, 2022 Objective: Infertility is defined as the failure to achieve a clinical pregnancy after twelve months of regular unprotected sexual intercourse. Both genetic and environmental factors affect infertility.
Aysel Kalaycı Yiğin +3 more
doaj +1 more source
BioMed Target Journal, 2023 Infertility is a disorder of the reproductive system characterized by a couple's inability to conceive after at least one year of regular, unprotected sexual activity. Approximately 15% of couples worldwide struggle with infertility.
Muhsin Jamil Abdulwahid +1 more
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Recognition of the Y chromosome in Turner syndrome using peripheral blood or oral mucosa tissue [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2021 Purpose Turner syndrome is defined as total or partial loss of the second sex chromosome in a phenotypically female patient. Due to the possibility of hidden mosaicism of fragments of the Y chromosome and development of gonadoblastoma, we evaluated the ...
Lene Garcia Barbosa +3 more
doaj +1 more source