Results 61 to 70 of about 9,826,894 (290)
About 10% of male infertile patients show abnormalities in spermatogenesis. The microdeletion of azoospermia factor a (AZFa) region of the Y chromosome is thought to be a cause of spermatogenic failure.
Takafumi MATSUMURA+4 more
doaj +1 more source
The Y chromosome: a blueprint for men’s health?
The Y chromosome has long been considered a ‘genetic wasteland’ on a trajectory to completely disappear from the human genome. The perception of its physiological function was restricted to sex determination and spermatogenesis.
Akhlaq Maan+7 more
semanticscholar +1 more source
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel+2 more
wiley +1 more source
Populations of Transcarpathia and Bukovina on the genetic landscape of surrounding regions
The territory of present-day Ukraine is subdivided into some regions with specific demographic and politic history. Nevertheless, the corresponding subdivision in genetic structure is not revealed in previous investigations: populations of Ukrainians ...
O. M. Utevska+5 more
doaj +1 more source
The asparagus genome sheds light on the origin and evolution of a young Y chromosome
Sex chromosomes evolved from autosomes many times across the eukaryote phylogeny. Several models have been proposed to explain this transition, some involving male and female sterility mutations linked in a region of suppressed recombination between X ...
A. Harkess+49 more
semanticscholar +1 more source
THE Y CHROMOSOME OF DROSOPHILA PSEUDOOBSCURA [PDF]
Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire +5 more sources
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche+2 more
wiley +1 more source
Repetitive DNA Sequences in the Human Y Chromosome and Male Infertility
The male-specific Y chromosome, which is well known for its diverse and complex repetitive sequences, has different sizes, genome structures, contents and evolutionary trajectories from other chromosomes and is of great significance for testis ...
Yong Xu, Qianqian Pang
doaj +1 more source
The study of human Y chromosome variation through ancient DNA
High throughput sequencing methods have completely transformed the study of human Y chromosome variation by offering a genome-scale view on genetic variation retrieved from ancient human remains in context of a growing number of high coverage whole Y ...
T. Kivisild
semanticscholar +1 more source
Review of the Y chromosome and hypertension
The Y chromosome from spontaneously hypertensive rats (SHR) has a locus that raises blood pressure 20-25 mmHg. Associated with the SHR Y chromosome effect is a 4-week earlier pubertal rise of testosterone and dependence upon the androgen receptor for the full blood pressure effect.
Ely, D., Turner, M., Milsted, A.
openaire +6 more sources