Results 81 to 90 of about 10,446,015 (290)

The asparagus genome sheds light on the origin and evolution of a young Y chromosome

Nature Communications, 2017
Sex chromosomes evolved from autosomes many times across the eukaryote phylogeny. Several models have been proposed to explain this transition, some involving male and female sterility mutations linked in a region of suppressed recombination between X ...
A. Harkess, A. Harkess, Jinsong Zhou, Chunyan Xu, J. Bowers, R. V. D. Hulst, Saravanaraj N. Ayyampalayam, F. Mercati, Paolo Riccardi, Paolo Riccardi, M. McKain, M. McKain, Atul Kakrana, Haibao Tang, Jeremy N. Ray, J. Groenendijk, S. Arikit, S. Arikit, S. Mathioni, S. Mathioni, Mayumi Nakano, Mayumi Nakano, Hongyan Shan, Alexa Telgmann-Rauber, A. Kanno, Zhen Yue, Haixin Chen, Wenqi Li, Yanling Chen, Xiangyang Xu, Yueping Zhang, Shaochun Luo, Helong Chen, Jianming Gao, Z. Mao, J. Pires, Meizhong Luo, D. Kudrna, R. Wing, B. Meyers, B. Meyers, K. Yi, H. Kong, Pierre Lavrijsen, F. Sunseri, A. Falavigna, Yin Ye, Yin Ye, J. Leebens-Mack, Guangyu E. Chen   +49 more
semanticscholar   +1 more source

An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility

The Journal of Reproduction and Development, 2019
About 10% of male infertile patients show abnormalities in spermatogenesis. The microdeletion of azoospermia factor a (AZFa) region of the Y chromosome is thought to be a cause of spermatogenic failure.
Takafumi MATSUMURA, Tsutomu ENDO, Ayako ISOTANI, Masaki OGAWA, Masahito IKAWA   +4 more
doaj   +1 more source

Detection of skewed X-chromosome inactivation in Fragile X syndrome and X chromosome aneuploidy using quantitative melt analysis. [PDF]

, 2015
Methylation of the fragile X mental retardation 1 (FMR1) exon 1/intron 1 boundary positioned fragile X related epigenetic element 2 (FREE2), reveals skewed X-chromosome inactivation (XCI) in fragile X syndrome full mutation (FM: CGG > 200) females ...
Amor, David J, Bui, Quang M, Francis, David, Godler, David E, Hagerman, Randi J, Herlihy, Amy S, Hopper, John L, Inaba, Yoshimi, Li, Xin, Metcalfe, Sylvia A, Schwartz, Charles E, Shi, Elva Z, Skinner, Cindy, Slater, Howard R   +13 more
core   +2 more sources

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

FEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman, Annika Egeler, Saskia Rödl, Johannes M. Herrmann   +3 more
wiley   +1 more source

The study of human Y chromosome variation through ancient DNA

Human Genetics, 2017
High throughput sequencing methods have completely transformed the study of human Y chromosome variation by offering a genome-scale view on genetic variation retrieved from ancient human remains in context of a growing number of high coverage whole Y ...
T. Kivisild
semanticscholar   +1 more source

A new robust diagnostic polymerase chain reaction for determining the mating status of female Anopheles gambiae mosquitoes. [PDF]

, 2007
The principal malaria vector in Africa, Anopheles gambiae, contains two pairs of autosomes and one pair of sex chromosomes. The Y chromosome is only associated with males and other Y chromosome-specific DNA sequences, which are transferred to women ...
Horton, Ashley, Knols, Bart G J, Lanzaro, Gregory C, Ng'habi, Kija R   +3 more
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

The Drosophila Y Chromosome Affects Heterochromatin Integrity Genome-Wide

bioRxiv, 2017
The Drosophila Y-chromosome is gene poor and mainly consists of silenced, repetitive DNA. Nonetheless, the Y influences expression of hundreds of genes genome-wide, possibly by sequestering key components of the heterochromatin machinery away from other ...
E. J. Brown, Alison H. Nguyen, D. Bachtrog   +2 more
semanticscholar   +1 more source

Populations of Transcarpathia and Bukovina on the genetic landscape of surrounding regions

Regulatory Mechanisms in Biosystems, 2015
The territory of present-day Ukraine is subdivided into some regions with specific demographic and politic history. Nevertheless, the corresponding subdivision in genetic structure is not revealed in previous investigations: populations of Ukrainians ...
O. M. Utevska, M. I. Chukhraeva, A. T. Agdzhoyan, L. A. Atramentova, E. V. Balanovska, O. P. Balanovsky   +5 more
doaj   +1 more source

Ten years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post-genome era. [PDF]

, 2019
The horse reference genome from the Thoroughbred mare Twilight has been available for a decade and, together with advances in genomics technologies, has led to unparalleled developments in equine genomics.
Bellone, R, Finno, Carrie, Petersen, J, Raudsepp, T   +3 more
core   +2 more sources