Chromosome Evolution in New World Monkeys (Platyrrhini) [PDF]
During the last decades, New World monkey (NWM, Platyrrhini, Anthropoideae) comparative cytogenetics has shed light on many fundamental aspects of genome organisation and evolution in this fascinating, but also highly endangered group of neotropical ...
Müller, Stefan +2 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
On the origin of crossover interference : a chromosome oscillatory movement (COM) model [PDF]
Background: It is now nearly a century since it was first discovered that crossovers between homologous parental chromosomes, originating at the Prophase stage of Meiosis I, are not randomly placed.
Maj A Hultén +2 more
core +1 more source
Investigating the role of nuclear myosin I in the low serum induced repositioning of chromosome 10 in interphase nuclei [PDF]
This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.The nucleus of mammalian cells has been proven to be highly organised.
Amira, Manelle
core +6 more sources
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Cytomolecular identification of individual wheat-wheat chromosome arm associations in wheat-rye hybrids [PDF]
Chromosome pairing in the meiotic metaphase I of wheatrye hybrids has been characterized by sequential genomic and fluorescent in situ hybridization allowing not only the discrimination of wheat and rye chromosomes, but also the identification of the
Megyeri, Mária +2 more
core +1 more source
Genetic identification of the golden jackal (Canis aureus Linnaeus, 1758) from Penza region
Background. The golden jackal ( Canis aureus ) is a species that has expanded its range across Eurasia in the 21st century, reaching the central regions of Russia and the Volga region.
Svetlana A. Lukonina, Oleg A. Ermakov
doaj +1 more source
Repetitive DNA Sequences in the Human Y Chromosome and Male Infertility
The male-specific Y chromosome, which is well known for its diverse and complex repetitive sequences, has different sizes, genome structures, contents and evolutionary trajectories from other chromosomes and is of great significance for testis ...
Yong Xu, Qianqian Pang
doaj +1 more source
On the peripheral location of the Y chromosome [PDF]
The location of the Y chromosome in metaphase spreads is studied in groups of (a) 96 normal males, (b) 17 Down's syndrome patients, and (c) 51 patients with Klinefelter's syndrome. The position of the Y is scored as either peripheral or nonperipheral using several of the traditional definitions found in the literature.
Kowalski, Charles J. +2 more
openaire +3 more sources

