Effect of vacuum pressure on Yamú fish (Brycon amazonicus) meat during cold storage [PDF]
This study aimed to assess the cryoprotectant effect of vacuum packaging (35 and 45 kPa) on cold preserved (0 °C and -18 °C) fillets of Yamú (Brycon amazonicus), during 5 days of storage. We analyzed the physicochemical and microbiological changes in the
Daniel Castañeda Valbuena +3 more
doaj +3 more sources
PD-L1 expression is regulated by ATP-binding of the ERBB3 pseudokinase domain [PDF]
How PD-L1 expression is regulated in cancer is poorly understood. Here, we report that the ATP-binding activity of ERBB3 pseudokinase regulates PD-L1 gene expression in colorectal cancers (CRCs).
Yamu Li +6 more
doaj +2 more sources
Spatial and temporal analysis of cumulative environmental effects of offshore wind farms in the North Sea basin [PDF]
The North Sea basin is one of the busiest maritime areas globally with a considerable number of anthropogenic pressures impacting the functioning of the marine ecosystem. Due to growing EU ambitions for the deployment of large offshore wind farm projects
Laura Florentina Gușatu +5 more
doaj +2 more sources
Nuclear translocation of p85β promotes tumorigenesis of PIK3CA helical domain mutant cancer [PDF]
The mechanisms behind the oncogenic role of the PIK3CA helical domain mutant is poorly understood. Here, the authors show that its oncogenic function depends on the release of p85β from mutated p110α, its translocation to the nucleus and the consequent ...
Yujun Hao +13 more
doaj +2 more sources
Novel Role for Tranilast in Regulating NLRP3 Ubiquitination, Vascular Inflammation, and Atherosclerosis [PDF]
Background Aberrant activation of the NLRP3 (nucleotide‐binding oligomerization domain, leucine‐rich repeat–containing receptor family pyrin domain‐containing 3) inflammasome is thought to play a causative role in atherosclerosis.
Suwen Chen +11 more
doaj +2 more sources
Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b [PDF]
The mechanisms underlying spatial and temporal control of cortical neurogenesis of the brain are largely elusive. Long non-coding RNAs (lncRNAs) have emerged as essential cell fate regulators.
Wei Li +10 more
doaj +2 more sources
LUBAC promotes angiogenesis and lung tumorigenesis by ubiquitinating and antagonizing autophagic degradation of HIF1α [PDF]
Hypoxia-inducible factor 1 (HIF1) is critically important for driving angiogenesis and tumorigenesis. Linear ubiquitin chain assembly complex (LUBAC), the only known ubiquitin ligase capable of catalyzing protein linear ubiquitination to date, is ...
Ying Jin +12 more
doaj +2 more sources
Transcriptome and proteome exploration to provide a resource for the study of Agrocybe aegerita. [PDF]
BACKGROUND: Agrocybe aegerita, the black poplar mushroom, has been highly valued as a functional food for its medicinal and nutritional benefits. Several bioactive extracts from A. aegerita have been found to exhibit antitumor and antioxidant activities.
Man Wang +11 more
doaj +2 more sources
Neutrophil extracellular traps induced by chemotherapy inhibit tumor growth in murine models of colorectal cancer [PDF]
Neutrophil extracellular traps (NETs), a web-like structure of cytosolic and granule proteins assembled on decondensed chromatin, kill pathogens and cause tissue damage in diseases. Whether NETs can kill cancer cells is unexplored. Here, we report that a
Yamu Li +24 more
doaj +2 more sources
This study aimed to evaluate the effect of cold storage on yamu fish meat (Brycon amazonicus). The methodology consisted of analyzing two temperatures (0}1.6°C and -8}1°C), two storage periods (13 and 61 hours) and two different sources (farm and river)
Daniel Castañeda +2 more
doaj +1 more source

