Results 1 to 10 of about 241 (112)

Effect of vacuum pressure on Yamú fish (Brycon amazonicus) meat during cold storage [PDF]

open access: yesBrazilian Journal of Food Technology, 2020
This study aimed to assess the cryoprotectant effect of vacuum packaging (35 and 45 kPa) on cold preserved (0 °C and -18 °C) fillets of Yamú (Brycon amazonicus), during 5 days of storage. We analyzed the physicochemical and microbiological changes in the
Daniel Castañeda Valbuena   +3 more
doaj   +3 more sources

PD-L1 expression is regulated by ATP-binding of the ERBB3 pseudokinase domain [PDF]

open access: yesGenes and Diseases, 2023
How PD-L1 expression is regulated in cancer is poorly understood. Here, we report that the ATP-binding activity of ERBB3 pseudokinase regulates PD-L1 gene expression in colorectal cancers (CRCs).
Yamu Li   +6 more
doaj   +2 more sources

Spatial and temporal analysis of cumulative environmental effects of offshore wind farms in the North Sea basin [PDF]

open access: yesScientific Reports, 2021
The North Sea basin is one of the busiest maritime areas globally with a considerable number of anthropogenic pressures impacting the functioning of the marine ecosystem. Due to growing EU ambitions for the deployment of large offshore wind farm projects
Laura Florentina Gușatu   +5 more
doaj   +2 more sources

Nuclear translocation of p85β promotes tumorigenesis of PIK3CA helical domain mutant cancer [PDF]

open access: yesNature Communications, 2022
The mechanisms behind the oncogenic role of the PIK3CA helical domain mutant is poorly understood. Here, the authors show that its oncogenic function depends on the release of p85β from mutated p110α, its translocation to the nucleus and the consequent ...
Yujun Hao   +13 more
doaj   +2 more sources

Novel Role for Tranilast in Regulating NLRP3 Ubiquitination, Vascular Inflammation, and Atherosclerosis [PDF]

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Aberrant activation of the NLRP3 (nucleotide‐binding oligomerization domain, leucine‐rich repeat–containing receptor family pyrin domain‐containing 3) inflammasome is thought to play a causative role in atherosclerosis.
Suwen Chen   +11 more
doaj   +2 more sources

Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b [PDF]

open access: yesProtein & Cell, 2019
The mechanisms underlying spatial and temporal control of cortical neurogenesis of the brain are largely elusive. Long non-coding RNAs (lncRNAs) have emerged as essential cell fate regulators.
Wei Li   +10 more
doaj   +2 more sources

LUBAC promotes angiogenesis and lung tumorigenesis by ubiquitinating and antagonizing autophagic degradation of HIF1α [PDF]

open access: yesOncogenesis
Hypoxia-inducible factor 1 (HIF1) is critically important for driving angiogenesis and tumorigenesis. Linear ubiquitin chain assembly complex (LUBAC), the only known ubiquitin ligase capable of catalyzing protein linear ubiquitination to date, is ...
Ying Jin   +12 more
doaj   +2 more sources

Transcriptome and proteome exploration to provide a resource for the study of Agrocybe aegerita. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Agrocybe aegerita, the black poplar mushroom, has been highly valued as a functional food for its medicinal and nutritional benefits. Several bioactive extracts from A. aegerita have been found to exhibit antitumor and antioxidant activities.
Man Wang   +11 more
doaj   +2 more sources

Neutrophil extracellular traps induced by chemotherapy inhibit tumor growth in murine models of colorectal cancer [PDF]

open access: yesThe Journal of Clinical Investigation
Neutrophil extracellular traps (NETs), a web-like structure of cytosolic and granule proteins assembled on decondensed chromatin, kill pathogens and cause tissue damage in diseases. Whether NETs can kill cancer cells is unexplored. Here, we report that a
Yamu Li   +24 more
doaj   +2 more sources

Microstructural changes and the effect on myofibril proteins in yamu (Brycon amazonicus) fish meat during cold storage

open access: yesAgronomía Colombiana, 2016
This study aimed to evaluate the effect of cold storage on yamu fish meat (Brycon amazonicus). The methodology consisted of analyzing two temperatures (0}1.6°C and -8}1°C), two storage periods (13 and 61 hours) and two different sources (farm and river)
Daniel Castañeda   +2 more
doaj   +1 more source

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