Results 51 to 60 of about 1,335,417 (310)

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Effects of Different Carbohydrate Levels in Diets on Growth Performance and Muscle Nutritive Value of Ying Carp and Scattered-Scaled Mirror Carp (Cyprinus carpio)

Aquaculture Nutrition
This experiment aimed to assess the dietary adaptation and utilization of high carbohydrate diets to Ying carp and scattered-scaled mirror carp (Cyprinus carpio), focusing on growth performance, muscle nutritive value, and nutrient metabolism. Ying carp (
Pengfei Xiao, Yunya Wu, Hang Sha, Xiangzhong Luo, Guiwei Zou, Hongwei Liang   +5 more
doaj   +1 more source

Satellite estimates of wide-range suspended sediment concentrations in Changjiang (Yangtze) estuary using MERIS data [PDF]

, 2010
The Changjiang (Yangtze) estuarine and coastal waters are characterized by suspended sediments over a wide range of concentrations from 20 to 2,500 mg l-1.
Salama, M.S., Verhoef, W., Salama, M.S.; id_orcid, Liu, X., Fang Shen, Yunxuan Zhou, Zhou, Y., Liu, Xiaoji, Xiaoli Liu, Wouter Verhoef, Mhd. Suhyb Salama, Shen, F.   +11 more
core   +1 more source

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

Advanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai, Jikuang Zhao, Chang Xue, Kailei Xu, Liang Yong, Zhuangwei Zhang, Yi Huang, Jianwei Shuai, Xianzhen Chen, Sheng Nie, Junpeng Xu   +10 more
wiley   +1 more source

Analysis of Gas–Liquid Phase Transition and Loss in Magnetic Fluids

Magnetochemistry
This study systematically investigates the gas–liquid phase transition heat transfer characteristics and volatilization loss behavior of magnetic liquid sealing devices under high-temperature and high-speed operating conditions.
Xianwei Jing, Ziran Feng, Ju Yang, Guangming Tian, Zhijun Guan   +4 more
doaj   +1 more source

Unlocking Li/Mg‐Based Photochemical Nitration Platforms for Anticancer Drug Discovery

Advanced Science, EarlyView.
Two low‐toxicity light main‐group metal photochemical systems based on lithium and magnesium are constructed for selective C(sp2)‐H (di)nitration of anilines. The obtained dinitrated products exhibit anti‐HCC (hepatocellular carcinoma) and anti‐KYSE30 cell activities, holding promise as novel antitumor candidates.
Qian Wan, Jiali Zhu, Shanshuo Liu, Luchuan Ou, Huizhen Wang, Yu Lan, Zhou Dong, Yihang Bai, Wei Yang, Shihan Liu, Yan Qiao, Shi‐Jun Li, Zhigang Ren, Linbin Niu   +13 more
wiley   +1 more source

Genome-wide identification and expression analysis of heat shock factors in Plantago fengdouensis under abiotic stresses

BMC Plant Biology
Plantago fengdouensis is a rare plant with extremely limited distribution, it once thrived on the central islands of the Yangtze River, where it was alternately exposed to flooding and high temperatures annually.
Linbao Li, Yang Su, Limengjie Wang, Jinhua Wu, Guangxin Zhang, Junchen Wang, Meixiang Hu, Weibo Xiang, Qianyan Liang, Ganju Xiang, Zhiqiang Xiao, Guiyun Huang, Di Wu   +12 more
doaj   +1 more source

Soil pH Amelioration Synergizes Carbon Accrual with Yield Gains Under Organic Substitution

Advanced Science, EarlyView.
Soil pH shifts towards neutrality in both acidic and alkaline soils under organic substitution. A global synthesis links pH amelioration to soil organic carbon accrual through enhanced microbial biomass after accounting for added organic carbon and its interaction with pH. This pH amelioration‐shared soil organic carbon accrual accounts for 5.1–8.6% of
Xunzhuo Dong, Yanzhong Yao, Bingbing Han, Yunyao Zhong, Benyi Li, Mengfei Li, Yunchao Dai, Zhaolei Li   +7 more
wiley   +1 more source

A QuEChERS-HPLC-MS/MS Method with Matrix Matching Calibration Strategy for Determination of Imidacloprid and Its Metabolites in Procambarus clarkii (Crayfish) Tissues

Molecules, 2021
We developed a method for determination of imidacloprid and its metabolites 5-hydroxy imidacloprid, olefin imidacloprid, imidacloprid urea and 6-chloronicotinic acid in Procambarus clarkii (crayfish) tissues using quick, easy, cheap, effective, rugged ...
Qiuhong Yang, Xiaohui Ai, Jing Dong, Yongtao Liu, Shun Zhou, Yibin Yang, Ning Xu   +6 more
doaj   +1 more source

PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma

Advanced Science, EarlyView.
PLOD1 interacts with ENO1 and limits its FBXW7‐dependent ubiquitination and proteasomal degradation through a mechanism requiring PLOD1 catalytic activity. ENO1 stabilization sustains glycolysis, promoting glioblastoma cell proliferation, migration, and temozolomide resistance.
Fen Xue, Dingkong Liang, Xin Chen, Fei Fan, Xiayun He   +4 more
wiley   +1 more source