Results 41 to 50 of about 5,592 (256)
LAMP4yaws: Treponema pallidum, Haemophilus ducreyi loop mediated isothermal amplification − protocol for a cross-sectional, observational, diagnostic accuracy study
BMJ Open, 2022 Introduction Yaws, caused by the bacterium Treponema pallidum subsp. pertenue, is a neglected tropical disease targeted for eradication by 2030. Improved diagnostics will be essential to meet this goal.Michael Marks, Tania Crucitti, Emma Michele Harding-Esch, Daniel Arhinful, Earnest Njih Tabah, Serges Tchatchouang, Oriol Mitja, Becca Louise Handley, Camila González-Beiras, Laud Antony Basing, Kouadio Aboh Hugues, Mohammed Bakheit, Lisa Becherer, Christina Ries, Nadine Borst, Simone Lüert, Sieghard Frischmann, Tamara Haerpfer, Emelie Landmann, Ivy Amanor, Aboubacar Sylla, Mireille S Kouamé-Sina, Jean P Ndzomo-Ngono, Adingra Tano, Patrick Awondo, Solange Ngazoa Kakou, Sara Eyangoh, Kennedy Kwasi Addo, Sascha Knauf +28 moredoaj +1 more sourceTopical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws.
PLoS Neglected Tropical Diseases, 2019 BackgroundGallium is a semi-metallic element known since the 1930s to have antimicrobial activity. This activity stems primarily from gallium's ability to mimic trivalent iron and disrupt specific Fe(III)-dependent pathways, particularly DNA synthesis ...Lorenzo Giacani, Lawrence R Bernstein, Austin M Haynes, B Charmie Godornes, Giulia Ciccarese, Francesco Drago, Aurora Parodi, Sefora Valdevit, Luca Anselmi, Carlo Francesco Tomasini, Arthur M Baca +10 moredoaj +1 more sourceComparative efficacy of low-dose versus standard-dose azithromycin for patients with yaws: a randomised non-inferiority trial in Ghana and Papua New Guinea
The Lancet Global Health, 2018 Summary: Background: A dose of 30 mg/kg of azithromycin is recommended for treatment of yaws, a disease targeted for global eradication. Treatment with 20 mg/kg of azithromycin is recommended for the elimination of trachoma as a public health problem ...Michael Marks, PhD, Oriol Mitjà, PhD, Christian Bottomley, PhD, Cynthia Kwakye, PhD, Wendy Houinei, DPH, Mathias Bauri, MPH, Paul Adwere, MPH, Abdul A Abdulai, MPH, Fredrick Dua, MD, Laud Boateng, MPH, James Wangi, MD, Sally-Ann Ohene, MPH, Regina Wangnapi, MD, Shirley V Simpson, MPhil, Helen Miag, HEO, Kennedy K Addo, ProfPhD, Laud A Basing, MPhil, Damien Danavall, BSc, Kai H Chi, MSc, Allan Pillay, PhD, Ronald Ballard, ProfPhD, Anthony W Solomon, PhD, Cheng Y Chen, PhD, Sibauk V Bieb, MAHM, Yaw Adu-Sarkodie, ProfPhD, David C W Mabey, ProfFRCP, Kingsley Asiedu, MPH, Michael Marks, Oriol Mitjà, Christian Bottomley, Cynthia Kwakye, Wendy Hounei, Mathias Bauri, Paul Adwere, Abdul A Abdulai, Fredrick Dua, Laud Boateng, James Wangi, Sayy-Ann Ohene, Regina Wangnapi, Shirley V Simpson, Helen Miag, Kennedy K Addo, Laud A Basing, Damien Danavall, Kai H Chi, Allan Pillay, Ronald Ballard, Anthony W Solomon, Cheng Y Chen, Sivuak V Bieb, Yaw Adu-Sarkodie, David CW Mabey, Kingsley Asiedu, Nsire Agana, Edwin Ampadu, Kwame Amponsah-Achiano, Asare Bediako, Michael Biredu, Kyei Faried, Ahmed Iddrisu, Nana K Kotey, George NY Yeboah, Philip El-Duah, Richard Phillips, Fred Binka, Frank Nyonator, Anthony Zunuo, Mercy A Ackumey, Ivy Amanor, Christian Bnosu, Sieghard Frischmann, Patrick Lammie, Diana Martin, Tun Ye, Eva Christophel, Alexandre Tiendrebeogo, Lasse Vestergard, Quique Bassat, Yazid Abdad, Henson Dima, Bethuel Kotty, Kaiok Mamore, Walerius Manup, Benson Olowau, Enoch O Agyei, David Agyemang, Ebenezer P Ako, Prince Antwi, Jane Darko, Ophelia O Darko, Phylis Darko, Bertha Duodu, Daniel Jabasi, Fuseini L Karim, Obed K Koomson, Bernard A Labri, John Nartey, Randsford Tamatey, Benjamin Yirenkyi, Mercy Arhin, Frank Biney, Juliana O Danso, Martin A Dei, Moses Djan, Samuel Sasu, Brefo A Solomon, Victor Torvinya, Hagar Amankwaah, James Baffoe, Moses Djan, Lydia Keteku, Kofi Kondobala, Rita D Lomotey, Augustina A Nartey, Paul Oppong, Millicent A Quainoo, Theophilus Abotsi, Dzighordi Agebshie, Amos Ameamu, Paul Angwaawie, Rose Ayibor, Margaret Mwingmendeli, John Nakodia, Amatus Nambagyira, Dominic Nanga, Nichola Tetteh, Augustine Wanaom +127 moredoaj +1 more sourceIntelligent Sky Guardians (InSkyGuard): An Aerial Robotic Swarm for Autonomous Detection and Entrapment of Rogue Multirotors
Advanced Robotics Research, EarlyView.Intelligent Sky Guardians (InSkyGuard) is introduced as a four‐drone swarm that autonomously detects, tracks, and safely captures rogue drones using a coordinated net system. Computer vision and leader–follower control architecture enable synchronized enclosure, while integrated failsafes enhance system reliability. Validated through closed‐environment Joshua Hastings, Levanya Dewanarayana, Iline Shaju, Haider Al‐Wizni, Sampson Marquis, Weicheng Huang, Pooya Sareh +6 morewiley +1 more sourceTacVerse: A Multisensor Dataset and Benchmark for Cross‐Sensor Vision‐Based Tactile Perception
Advanced Robotics Research, EarlyView.TacVerse provides a controlled benchmark of 106 800 tactile images from seven vision‐based tactile sensors across shape classification, grating classification, and force regression. Direct cross‐sensor transfer reveals substantial sensor‐shift degradation, with grating and force perception more affected than shape recognition.Lan Wei, Gurmeher Khurana, Sirine Bhouri, Wenhao Hong, Zeyuan Xin, Qingzheng Cong, Wen Fan, Yanzheng Xiang, Dandan Zhang +8 morewiley +1 more sourceKnowledge, attitudes and practices towards yaws in endemic areas of Ghana, Cameroon and Côte d'Ivoire.
PLoS Neglected Tropical DiseasesYaws, caused by Treponema pallidum ssp. pertenue, remains a significant public health concern in tropical regions of West Africa and the South Pacific, primarily affecting children in remote areas with limited access to hygiene and sanitation.Camila González Beiras, Adingra Tano Kouadio, Becca Louise Handley, Daniel Arhinful, Serges Tchatchouang, Ahouansou Stanislas Sonagnon Houndji, Eric Tettey Nartey, Dolphine Osei Sarpong, Gely Menguena, Philippe Ndzomo, Laud Anthony Basing, Kouadio Aboh Hugues, Ivy Brago Amanor, Mohammed Bakheit, Emelie Landmann, Patrick Awondo, Claudia Müller, Tania Crucitti, Nadine Borst, Lisa Becherer, Simone Lüert, Sieghard Frischmann, Aboubacar Sylla, Mireille S Kouamé-Sina, Emma Michèle Harding-Esch, Sascha Knauf, Oriol Mitjà, Sara Eyangoh, Kennedy Kwasi Addo, Solange Ngazoa Kakou, Michael Marks +30 moredoaj +1 more sourceA cross-sectional study of 'yaws' in districts of Ghana which have previously undertaken azithromycin mass drug administration for trachoma control.
PLoS Neglected Tropical Diseases, 2015 Yaws, caused by Treponema pallidum ssp. pertenue, is reportedly endemic in Ghana. Mass distribution of azithromycin is now the cornerstone of the WHO yaws eradication campaign.Rosanna Ghinai, Philip El-Duah, Kai-Hua Chi, Allan Pillay, Anthony W Solomon, Robin L Bailey, Nsiire Agana, David C W Mabey, Cheng-Yen Chen, Yaw Adu-Sarkodie, Michael Marks +10 moredoaj +1 more sourcePerformance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue
Advanced Science, EarlyView.This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...Leendert‐Jan W. Ligtenberg, Thijs J. van der Burg, Stijn Y. Kolkman, Santiago Saavedra Castano, David Fernandez Rivas, Anke Klingner, Roger M. L. M. Lomme, Lucas S. Joziasse, Dorothee Wasserberg, H. Remco Liefers, Doron Ben Ami, Udi Sadeh, Oded Shoseyov, Giulio Dagnino, Pascal Jonkheijm, Jurgen J. Fütterer, Stefano Stramigioli, J. Frank W. Nijsen, Michiel C. Warlé, Islam S. M. Khalil +19 morewiley +1 more source