Results 151 to 160 of about 66,760,976 (279)

Global and national trends in years of life lost and years lived with disability caused by three common gastrointestinal cancers from 1990 to 2019. [PDF]

BMC Gastroenterol, 2022
Yu D, Ou Z, Zhang W, He H, Li Y, He W, Zhang M, Gao Y, Wu F, Chen Q.   +9 more
europepmc   +1 more source

RBM12 Maintains Glioma Stem Cells by Activating Amino Acid‐Dependent mTORC1 Signaling via SLC7A5 mRNA Stabilization

Advanced Science, EarlyView.
This study shows that in glioma stem cells (GSCs), RBM12 recruits ALKBH5 to remove m6A from SLC7A5 transcripts, thereby enhancing mRNA stability, which elevates large neutral amino acid (LNAA) levels and activates mTORC1, promoting GSC proliferation, self‐renewal, and tumor growth.
Hong Lei, Wenlong Luo, Shu Zhou, Lihao Wan, Peng Ling, Zhihua Huang, Zhihua Qian, Chenfei Lu, Mengyue Guo, Zhen Xue, Jun Qin, Ningwei Zhao, Jianghong Man, Wenchao Zhou, Zhiqiang Dong, Shutong Xu, Zhipeng Zhou, Xiuxing Wang, Weiwei Tao   +18 more
wiley   +1 more source

The impact of COVID-19: consequences of a 3-Year struggle in Iran

BMC Infectious Diseases
Background The disability-adjusted life year (DALY) approach gives policymakers a clear understanding of the scale of the health issue. This study aimed to estimate DALYs attributed to coronavirus disease 2019 (COVID-19) for the population of Bushehr ...
Habib Omranikhoo, Hedayat Salari, Khosro Keshavarz, Marziyeh Rajabi, Mehdi Rezaee   +4 more
doaj   +1 more source

Global, regional, and national time trends in incidence, prevalence, years lived with disability for uterine fibroids, 1990-2019: an age-period-cohort analysis for the global burden of disease 2019 study. [PDF]

BMC Public Health, 2023
Lou Z, Huang Y, Li S, Luo Z, Li C, Chu K, Zhang T, Song P, Zhou J.   +8 more
europepmc   +1 more source

A Portable Soft Robotic Glove with Fully Functional Thumb Assistance for Complex Dexterous Fine Motor Skills

Advanced Science, EarlyView.
A portable, sensorized, and controlled dexterous thumb‐enhanced glove helps stroke survivors swipe phones, twist caps, and perform other tasks. It is based on a powerful continuously, segmented origami dual chamber actuator to achieve active thumb CMC and MCP joint assistance and passively extend the IP joint.
Disheng Xie, Zhen Wang, Zhongping Ye, Minghao Liu, Xiangqian Shi, Shuk Fan Tong, Jianbin Liu, Chuanbin Mao, Thomas W. Leung, Haitao Liu, Raymond Kai‐yu Tong   +10 more
wiley   +1 more source

The prevalence and years lived with disability of asthma in children under 5 years old in Sichuan Southwest China, 1990-2019: A cross-sectional study. [PDF]

Front Pediatr, 2022
Luo Y, Bao L, Wang M, Guo H.
europepmc   +1 more source

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source

Burden and causes of anemia in Vietnam: insights from the global burden of disease data

BMC Public Health
Background Anemia is a significant global health issue, impacting 1.92 billion people and ranking as a leading cause of disability. It is marked by low hemoglobin levels, which hinder oxygen delivery to vital organs and result from causes such as ...
Deepak Kumar Behera, Dil B. Rahut, Snehasish Tripathy, Sapna Negi   +3 more
doaj   +1 more source

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

Advanced Science, EarlyView.
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi, Xinmei Li, Yufan Hao, Qiaoyu Wu, Yuji Yu, Siyu Li, Nuo Xu, Yi‐Hsuan Wu, Eunhye Lee, Chi Chang, Emily Hu, Ying Lu, Elizabeth Delzell, Ann W. Hsing, Shankuan Zhu   +14 more
wiley   +1 more source

Beyond disability-adjusted life years (DALYs) : developing indicators to assess the impact of public health interventions on the lives of people with disabilities [PDF]

This paper proposes two measures for assessing the impact of interventions on the lives of disabled people, the Activity Limitation Score (ALS) and the Participation restriction Score (PRS).
Mont, Daniel, Loeb, Mitchell
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