Results 181 to 190 of about 384,421 (314)

GBD 2015: migraine is the third cause of disability in under 50s [PDF]

, 2016
Steiner, TJ, Stovner, LJ, Vos, T
core   +1 more source

Incidence, Morbidity and years Lived With Disability due to Type 2 Diabetes Mellitus in 204 Countries and Territories: Trends From 1990 to 2019. [PDF]

Front Endocrinol (Lausanne), 2022
Zhu R, Zhou S, Xia L, Bao X.
europepmc   +1 more source

Uncertainty of Years Lived with Disability in Child Mental Disorders Attributable to Data Sources: Estimates from a Population Survey and a National Health Facility Dataset

, 2018
Yi‐Lung Chen, Raymond Nien-Chen Kuo, Susan Shur‐Fen Gau   +2 more
openalex   +1 more source

Peer Review #1 of "Trends in the incidence, prevalence and years lived with disability of facial fracture at global, regional and national levels from 1990 to 2017 (v0.1)"

, 2021

openalex   +1 more source

IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

Advanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang, Qingchen Zhang, Yanrui Chen, Dapeng Yu, Ronghan Liu, Jianning Kang, Xiang Fang, Ying Zhang, Hong Bian, Yanxin Zhao, Yongcheng Yin, Ce Zhang, Yanfei Jia, Qingfa Chen, Yuepeng Fang, Shang Li, Fang Li, Zhengxin Jin, Bin Ning   +18 more
wiley   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Identifying Potential Vulnerability to Long COVID Through Global‐to‐Local Inequalities in Years Lived With Disability Attributed to COVID‐19, 2020–2021, Across 920 Locations [PDF]

Dan Shan, Wenyi Jin, Fei Li, Chengliang Yang, You Zeng, Ruiling Xie, Qingjia Zeng, Yi Chen, Haowei Wang, Christine Linehan, Claire Chenwen Zhong, Qiaoyu Shao, Xiaozhu Liu, Wen Chen, Tongrui Shang, Dong Wang, Yuanyuan Wan, Ningning Wu, Minzhi Lv, Zhihui Li, Yue Qiu, Wei Wang, Xian Shao, Ruhai Bai, Lili Zheng, Baozhen Huang, Weize Xu, Changchang Li, Zimeng Wu, Guangyao Cai, Yuanyuan Chen, Ying Wang, Shuang Hu, Liang Zhang, Lerong Chen, Jianhua Huang, Scott J. Tebbutt, Ting Luo, Queran Lin, Salman Rawaf, Azeem Majeed, for the GBD 2021 Long COVID Impact and Inequality Collaborators   +41 more
openalex   +1 more source

Global Trends in Death, Years of Life Lost, and Years Lived With Disability Caused by Breast Cancer Attributable to Secondhand Smoke From 1990 to 2019. [PDF]

Front Oncol, 2022
Ou Z, Gao Y, Jiang D, Cui J, Ren Y, Tang S, Duan D, Yu D, Wang Z.   +8 more
europepmc   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source