Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang +12 more
wiley +1 more source
Overview of the Kansas Department for Aging and Disability Services
"January 18, 2017."<br>Presentation before the Kansas Legislature, House Social Services Budget Committee Meeting, presented by Secretary Tim Keck, Kansas Department for Aging and Disability Services.Presentation giving an overview of the Kansas ...
Keck, Timothy E., 1966-
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Temporal Trends and Sex Differences in Disability-Adjusted Life Years (DALYs), Years Lived With Disability (YLDs), and Years of Life Lost (YLLs) Attributable to Infectious Diseases in Afghanistan: Global Burden of Disease 2023 Estimates, 1999-2023. [PDF]
Khan A, Tidman M.
europepmc +1 more source
Correction: Epidemiology of facial fractures: incidence, prevalence and years lived with disability estimates from the Global Burden of Disease 2017 study. [PDF]
europepmc +1 more source
Behavioral Coping With Food Price Inflation: Patterns Among U.S. Households
ABSTRACT Recent food price inflation has placed substantial pressure on household budgets, food security, and mental well‐being. Using Household Pulse Survey data, we combine k‐modes clustering and Double Machine Learning to identify distinct household coping groups and examine differences in how households respond to rising food prices across groups ...
Yuxiang Zhang, Yizao Liu
wiley +1 more source
NDS state of the disability sector report 2015
Most disability service providers are cautiously optimistic and plan to grow in the next six months; but a high proportion think that government agencies are not working closely enough with the sector to implement the NDIS successfully.
National Disability Services
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Temporal trends and health inequalities in global, regional, and national years lived with disability of severe periodontitis from 1990 to 2021. [PDF]
Zhang S +6 more
europepmc +1 more source
This consensus describes the protective effect and safety of influenza and pneumococcal vaccines, and vaccination recommendations, aiming to promote the vaccination rate, better play the role of vaccines in preventing influenza and pneumococcal diseases, and reduce the occurrence of respiratory infections and related serious complications in elderly ...
Lijing Wang +31 more
wiley +1 more source
Global prevalence, incidence, and years lived with disability (YLDs) of osteoarthritis: trends from 1990 to 2021 and projections to 2050. [PDF]
Chen M +9 more
europepmc +1 more source
Impact of Acute Functional Decline on Frailty and Mortality in Acutely Hospitalized Older Persons
Older persons with acute functional decline are often severely frail. Male sex, cognitive impairment, diabetes mellitus type 2, cancer, hearing impairment, and nursing home living increase the risk of severe frailty or death and should be considered when person‐centered care is planned for hospitalized older people.
Ali Vahedi +5 more
wiley +1 more source

