Results 121 to 130 of about 3,118,924 (388)

Years of life lost through Down's syndrome. [PDF]

open access: yesJournal of Medical Genetics, 1979
A congenital genetic condition does not act either as a cause of death or at the time of death only. Hence, years of life lost through such a conditon cannot be calculated in the same way as for a conventional cause of death. The main difference is that a cause of death acting at age x cuts off as many years of life as the dead person might otherwise ...
openaire   +2 more sources

Ambient Temperature and Years of Life Lost: A National Study in China

open access: yesThe Innovation, 2020
Summary Although numerous studies have investigated premature deaths attributable to temperature, effects of temperature on years of life lost (YLL) remain unclear.
Tao Liu   +32 more
semanticscholar   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Narratives of art-making in chronic fatigue syndrome/ myalgic encephalomyelitis: Three case studies [PDF]

open access: yes, 2006
This paper explores the narratives of three women who had lived with severe chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) for many years, and who engaged in art-making as a leisure activity rather than for psychotherapy.
Reynolds, F
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Eflornithine is a cost-effective alternative to melarsoprol for the treatment of second-stage human West African trypanosomiasis in Caxito, Angola. [PDF]

open access: yes, 2008
OBJECTIVE: To compare the cost-effectiveness of eflornithine and melarsoprol in the treatment of human African trypanosomiasis. METHOD: We used data from a Médecins Sans Frontières treatment project in Caxito, Angola to do a formal cost-effectiveness ...
Adam   +23 more
core   +2 more sources

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Mortalidad y años potenciales de vida perdidos por causas externas: Colombia 1998-2015 [PDF]

open access: yes, 2018
Introduction: The external causes of mortality are constituted as a public health problem which affect young population, have social relevance, are avoidable and their impact is reducible in the long term. Objective: To describe the behavior of mortality
Cardona-Arango, Doris   +1 more
core   +3 more sources

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Financial aspect of indian suicides in 2015

open access: yesIndian Journal of Psychological Medicine, 2018
Background: There is an increasing need for cost computation of every aspect of human behavior for planning. Objective: This objective of the study was to compute the cost of suicide in India in 2015.
Poduri Gopala Sarma
doaj   +1 more source

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