Results 141 to 150 of about 1,465,723 (294)

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

Angewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao, Leyao Chen, Karin Steffen, Henrik Schweder, Birgit Schreckenberger, Shu‐Ming Li, Ben Auxier, Antonis Rokas, Reinhard Fischer   +8 more
wiley   +2 more sources

Particles, Objects, and Physics [PDF]

, 2005
This thesis analyses the ontological nature of quantum particles. In it I argue that quantum particles, despite their indistinguishability, are objects in much the same way as classical particles. This similarity provides an important point of continuity
Justin C. Pniower, Pniower, Justin C, Pniower, Justin   +2 more
core  

Donor‐Cell Senescence Redirects PINK1‐Marked Mitochondrial Cargo From Mitophagy to Microvesicle Transfer Through SUMO3‐Stabilized HSPA9

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicle therapies have been developed for tissue repair, but how donor‐cell senescence reshapes vesicle‐mediated mitochondrial transfer remains unclear. Here, we show that senescent adipose‐derived stem cells (ADSCs) redirect damaged mitochondria into microvesicles (MVs), converting protective vesicles into pro‐degenerative ...
Zixuan Ou, Mingke Zhao, Zhiwei Ling, Lianqi Peng, Bide Tong, Huaizhen Liang, Hongchuan Wang, Di Wu, Yifan Du, Zhi Du, Shihao Zhang, Yuyuan Jia, Yifan Qian, Gan Xu, Liuliang He, Gang Li, Shun Zhang, Lei Tan, Kun Wang, Xiaobo Feng, Cao Yang, Zhiwei Liao   +21 more
wiley   +1 more source

Yeast-gene-measurements

Yeast gene position ...
Venkata Aditya Satvik Bhamidi (17699916)
core   +1 more source

Gradient‐Oxidized Bacterial Cellulose for Self‐Sustained Soil Moisture Sensing

Advanced Science, EarlyView.
An asymmetric encapsulated bacterial cellulose device integrates a gradient‐oxidized BC framework with a LiCl‐doped Ecoflex hygroscopic layer, enabling self‐powered soil moisture monitoring through directional ion transport. The device sustains stable hydrovoltaic output, supports deep‐learning humidity classification, and fully biodegrades in soil ...
Nan Zhou, Jing Li, Xiang Xu, Senyuan Ye, Bin Chen, Shuang Wu, Duo Xu, Keshuai Liu, Chong Gao, Weilin Xu, Can Ge   +10 more
wiley   +1 more source

Recognition of yeast β-glucan particles triggers immunometabolic signaling required for trained immunity

iScience
Summary: Fungal β-glucans are major drivers of trained immunity which increases long-term protection against secondary infections. Heterogeneity in β-glucan source, structure, and solubility alters interaction with the phagocytic receptor Dectin-1 and ...
Cian J.H. Horneck Johnston, Anna E. Ledwith, Mimmi L.E. Lundahl, Hugo Charles-Messance, Emer E. Hackett, Simon D. O’Shaughnessy, Jonah Clegg, Hannah Prendeville, John P. McGrath, Aaron M. Walsh, Sarah Case, Hollie Austen Byrne, Parth Gautam, Elaine Dempsey, Sinead C. Corr, Frederick J. Sheedy   +15 more
doaj   +1 more source

Synthetic Particulate Subunit Vaccines Co‐Delivering Multiple Antigens Induce Protective Immunity Against Melioidosis

Advanced NanoBiomed Research, EarlyView.
Engineered endotoxin‐free Escherichia coli were used to assemble poly(3‐hydroxybutyrate) (PHB) biopolymer particles displaying multiple conserved Burkholderia pseudomallei antigens via PhaC‐mediated surface presentation. Following formulation with poly(I:C), the particulate vaccines induced antigen‐specific humoral and cellular immune responses ...
Md. Tanvir Kabir, Shuxiong Chen, Justine B. Bendo, Ashley Johnson, Aleksandra W. Debowski, Mitali Sarkar‐Tyson, Bernd H. A. Rehm   +6 more
wiley   +1 more source

Interaction between long and short particles of tobacco rattle virus [PDF]

, 1972
Tobacco rattle virus is a rod-shaped multiparticle virus.Short particles alone are not infectious, long ones are but give rise to the formation of incomplete virus. Mixtures of long and short particles induce the formation of complete virus.
Huttinga, H.
core  

THE HETEROLOGIC INDUCTION OF THE EXPRESSION OF THE YEAST TuI-ELEMENT AND THE POSSIBILITY OF USE OF THE TRANSPOSON-CARRYING VIRUS-SIMILAR PARTICLES FOR THE TRANSFER IN THE YEAST FOREIGN GENES

, 1996
The purpose of the work: studying the expression of the Drosophila retrotransposons in the yeast cells and heterologic activation of the yeast transposon TuI expression, the search for the possible mechanisms of this activation and investigation of ...
Kidgotko, Oxana Valerievna
core  

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +1 more source