Results 41 to 50 of about 33,608 (178)

Evaluating effectiveness of risk minimization through healthcare professional surveys: A review of post‐authorization studies, 2022–2024

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Risk minimization measures (RMMs) are key regulatory tools to ensure safe medicinal product use. Regulatory guidelines recommend pre‐specifying the targets, or ‘thresholds’, for assessing RMM effectiveness. We aimed to review recent industry‐sponsored post‐authorization safety studies (PASS) that evaluated the effectiveness of RMMs ...
Kexin Zhu, William A. Blumentals, Froilan G. Celzo, G. Caleb Alexander, Lingyun Zhou, Juhaeri Juhaeri, Corinne Jouquelet‐Royer, Jian‐Yu E   +7 more
wiley   +1 more source

Yellow Fever Vaccination: An Issue for Non-endemic Tropical Countries

International Journal of Travel Medicine and Global Health, 2018
Yellow fever is an important mosquito-borne infection. This disease is endemic in several tropical countries in Africa and South America. It is serious and can result in death. This disease can be prevented, and the best preventive measure is vaccination.
Viroj Wiwanitkit
doaj   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Cross‐protective effect of a multicomponent fusion protein vaccine during a natural episode of Streptococcus zooepidemicus respiratory disease in ponies

Equine Veterinary Journal, EarlyView.
Abstract Background Streptococcus equi subspecies zooepidemicus is a highly diverse opportunistic pathogen of horses, associated with respiratory disease and endometritis. Objectives To characterise S. zooepidemicus isolates recovered from young ponies during a natural episode of respiratory disease, and to determine if vaccination with Strangvac®, a ...
Romain Paillot, J. Richard Newton, Sonia Gonzalez Medina, Sara Frosth, Lars Frykberg, Margareta Flock, Bengt Guss, Jan‐Ingmar Flock, Andrew S. Waller   +8 more
wiley   +1 more source

Vaccination in pediatric transplantation—General recommendations. A position paper by the European Reference Network TransplantChild

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Infectious diseases remain a leading cause of morbidity and mortality among pediatric transplant recipients, despite significant advances in transplantation management. Vaccination is the most effective strategy to prevent infections; however, its efficacy is hindered in solid organ transplant (SOT) and hematopoietic stem cell transplant (HSCT)
Valeria Casotti, Francesco Saglio, Adriana Balduzzi, Peter Barany, Vibeke Brix Christensen, Simona Buelli, Daniele Donà, Maja Klaudel‐Dreszler, Sara Mosca, Andrea Pietrobattista, Michele Pinon, Giusy Ranucci, Lars Wennberg, Lorenzo D'Antiga, ERN TransplantChild Working Group, Claudia Vittori, Manuela Tumino, B. Ruben Brandsema, Lisa Swartling, Silvia Garazzino, Carlo Pace Napoleone, Kai Lehmberg, Isabella Guzzo, Charlotte Roy, Nicola Pradegan, Silvia Simo Nebot, Maria Herthelius, Angelo Mazza, Enrico Aidala, Oleg Godik, Victoria Bordon Cueto De Braem, Marco Busutti, Emily Claire Argento, Marc Garcia Lorenzo, Timo Jahnukainen, Zoryana Ivanyuk   +35 more
wiley   +1 more source

Designing a multi-epitope vaccine against yellow fever virus using immunoinformatics approaches

Open Medicine
Yellow fever virus (YFV) is a mosquito-borne pathogen causing severe hemorrhagic fever in tropical and subtropical regions. This study aimed to design and evaluated a multi-epitope subunit vaccine against yellow fever virus using immunoinformatics and ...
Naveed Muhammad, Asim Muhammad, Aziz Tariq, Toheed Muhammad, Athar Aroosa, Majeed Muhammad Nouman, Khan Ayaz Ali, Alharbi Maha, Shami Ashwag, Alwethaynani Maher S., Almsaud Mai M, Al-Joufi Fakhria A.   +11 more
doaj   +1 more source

Controvérsias sobre a ampliação das áreas com vacinação de rotina contra a febre amarela no Brasil

Cadernos de Saúde Pública
Resumo: Febre amarela é uma doença viral potencialmente grave, transmitida por mosquitos Haemagogus, Aedes e Sabethes. A vacinação é a medida mais importante para a sua prevenção e controle.
Tatiana Guimarães de Noronha, Luiz Antonio Bastos Camacho   +1 more
doaj   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Antibody response to 17D yellow fever vaccine in Ghanaian infants

Bulletin of the World Health Organization, 2001
OBJECTIVE: To assess the seroresponses to yellow fever vaccination at 6 and 9 months of age; assess any possible adverse effects of immunization with the 17D yellow fever vaccine in infants, particularly at 6 months of age.
Osei-Kwasi Mubarak, Dunyo S.K., Koram K.A., Afari E.A., Odoom J.K., Nkrumah F.K.   +5 more
doaj  

Tick‐Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme—For Whom, When and Where?

Acta Paediatrica, EarlyView.
ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley   +1 more source