Results 101 to 110 of about 66,826 (220)
ABSTRACT Complement temporal activation kinetics, activation pathways, and their relationship with thromboinflammation and antibody responses in severe vaccination‐COVID‐19 remains unclear. Based on a vaccinated‐infected cohort, we analyzed complement immune responses across mild to critical COVID‐19 cases by a dynamic model.
Jinpeng Cao +16 more
wiley +1 more source
THE PRESERVATION OF YELLOW FEVER VIRUS [PDF]
A W, Sellards, E, Hindle
openaire +2 more sources
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng +8 more
wiley +1 more source
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Abstract Understanding the frequency and socio‐ecological drivers of contacts between humans and non‐human primates (NHPs) is crucial for enhancing coexistence that favours NHP conservation, while limiting negative consequences such as aggressions and cross‐species disease transmission.
Cristina Caparrós‐Vallcorba +3 more
wiley +1 more source
ABSTRACT Purpose Adverse drug reactions (ADRs) present significant obstacles for healthcare systems, impacting both patient safety and the effectiveness of treatments. Despite this, there is a scarcity of research on ADR reports in Sierra Leone, especially over long periods.
Isatu Jalloh +4 more
wiley +1 more source
The Cinderella tree, Quillaja saponaria – A soap story
Our current understanding of plants has been shaped by the entwining of different cultures. The Chilean soapbark tree, traditionally valued as a source of natural soap, was shown by serendipitous research in France in the 1900s to produce compounds that can boost the immune response to vaccines.
Anne Osbourn
wiley +1 more source
Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana +4 more
wiley +1 more source
Structural Basis of MERS‐CoV Receptor Interactions and Antibody Neutralisations
ABSTRACT Increasing outbreaks of coronaviruses underscore the importance of antivirals and vaccines that can combat a wide range of coronaviruses. Neutralising antibodies (nAbs), along with vaccines and small‐molecule drugs, are among the most promising treatments and prevention options against coronaviruses.
Edem Gavor +5 more
wiley +1 more source
Characteristics, Motivation, and Challenges of Global Research on Dengue Vaccination
ABSTRACT Due to the sharp increase in dengue infections in recent years, developing effective and regionally adapted vaccines is imperative. This requires research strategies aimed at vaccines that are free of side effects and effective for all four serotypes.
Doris Klingelhöfer +5 more
wiley +1 more source

