Computational modelling and in vitro liver cell experiments indicate that medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency causes an accumulation of (especially medium‐chain) acyl‐CoAs at the cost of free CoA (CoASH). A substantial decrease in CoASH impairs flux through many pathways essential for energy homeostasis.
Ligia Akemi Kiyuna +17 more
wiley +1 more source
Yellow Fever Virus (YFV) Detection in Different Species of Culicids Collected During an Outbreak in Southeastern Brazil, 2016-2019. [PDF]
Caleiro GS +9 more
europepmc +1 more source
The Behavior of the Virus of Yellow Fever in Monkeys and Mice [PDF]
openaire +2 more sources
Toxigenic Salmonella enterica exocytose the typhoid toxin during infection causing host cell DNA damage, which activates a Type‐1 Interferon‐like response characterised by interferon‐stimulated gene 15 (ISG15) expression. ISG15 was required for host cell survival during Interferon responses and suppressed intracellular growth of Salmonella. Thus, ISG15
Daniel S. Stark +11 more
wiley +1 more source
Potential Antiviral Compounds from <i>Hippeastrum puniceum</i> Bulb Against Yellow Fever Virus: Bioassay-Guided Fractionation and <i>In Silico</i> Pharmacokinetic Analysis. [PDF]
Flores-Souza E +11 more
europepmc +1 more source
Trap performance: Mosquito Magnet® captured significantly more mosquitoes overall, while BG‐Sentinel showed greater species evenness and was more effective for Culex pipiens s.l. and broader species representation. Spatial variation: Mosquito abundance and species composition varied significantly between wetlands, highlighting the importance of site ...
Alexander G. C. Vaux +7 more
wiley +1 more source
A single residue in domain II of envelope protein of yellow fever virus is critical for neutralization sensitivity. [PDF]
Lou Y-N +7 more
europepmc +1 more source
Spreading Speed for a Vector‐Borne Disease System on Non‐Coincident Straight Infinite Cylinders
ABSTRACT Vector‐borne diseases remain an increasing global public health concern. In this work, we investigate the spreading speed of vector‐borne disease via a four‐component reaction–diffusion system posed on non‐coincident straight infinite cylinders, which stands for an unconventional spatial configuration.
Arnaud Ducrot +2 more
wiley +1 more source
In Vivo Characterization and Tissue Tropism of a Wild-Type Yellow Fever Virus Isolate from the 2017-2018 Brazilian Outbreak in C57BL/6 IFNAR1<sup>-/-</sup> Mice. [PDF]
Cruz ALC +14 more
europepmc +1 more source
The development and validation of a microneutralization assay for the detection and quantification of anti-yellow fever virus antibodies in human serum. [PDF]
Fries K +7 more
europepmc +1 more source

