Results 41 to 50 of about 72,519 (291)

Advanced Yellow Fever Virus Genome Detection in Point-of-Care Facilities and Reference Laboratories

, 2012
Reported methods for the detection of the yellow fever viral genome are beset by limitations in sensitivity, specificity, strain detection spectra, and suitability to laboratories with simple infrastructure in areas of endemicity.
Nakoune, Emmanuel R, Mendez, Jairo A., Nakoune, Emmanuel Rivalyn, Yillah, Jasmin, Weidmann, Manfred, Domingo, Cristina, Patel, Pranav, Mendez, Jairo A, Niedrig, Matthias   +8 more
core   +1 more source

Zika virus infection, associated microcephaly, and low yellow fever vaccination coverage in Brazil: is there any causal link?

Journal of Infection in Developing Countries, 2016
Introduction: Since the end of 2014, Zika virus (ZIKV) infection has been rapidly spreading in Brazil. Methodology: To analyze the possible association of yellow fever vaccine with a protective effect against ZIKV-related microcephaly, the following ...
Luciano Pamplona de Góes Cavalcanti, Pedro Luiz Tauil, Carlos Henrique Alencar, Wanderson Oliveira, Mauro Martins Teixeira, Jorg Heukelbach   +5 more
doaj   +1 more source

Risk of yellow fever virus transmission in the Asia-Pacific region

Nature Communications, 2020
Yellow fever is absent from the Asia/Pacific region, despite presence of the mosquito vector. Here, the authors demonstrate that mosquitoes collected from field sites across the region are capable of transmitting yellow fever virus, indicating that ...
Lucy de Guilhem de Lataillade, Marie Vazeille, Thomas Obadia, Yoann Madec, Laurence Mousson, Basile Kamgang, Chun-Hong Chen, Anna-Bella Failloux, Pei-Shi Yen   +8 more
doaj   +1 more source

SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening

Advanced Science, EarlyView.
Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen, Jiaqi Yu, Jing Xu, Lingqi Chen, Ninghao Zhang, Wenrui Li, Runmin Zeng, Xiaomin Luo, Yiqun Chang, Jiayin Lai, Wenshi Huang, Xiaochen Liang, Ting Zhao, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Xueqin Huang, Haibo Zhou, Junxia Zheng   +20 more
wiley   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source

Identification of the effect of lycopene on the inhibition of yellow fever-causing flavivirus by studying microarray gene expression data

Journal of Current Oncology and Medical Sciences, 2022
Introduction: Yellow fever virus causes systemic disease of the liver, kidneys, myocardium and hemorrhage, which are high incidence and mortality. Lycopene is one of the effective antioxidants used to prevent the growth of cancerous tumors.
Gholamreza Dadashi Oranj
doaj  

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Seroprevalence of some Arboviruses among Pregnant Women in Ibadan, Southwestern, Nigeria

International Journal of Infectious Diseases, 2022
Purpose: To determine the seroprevalence of some arboviruses among pregnant women attending antenatal clinic in Ibadan, Nigeria. Methods & Materials: Sera of 36 ELISA anti-Zika virus immunoglobulin M (IgM)- and/or immunoglobulin G (IgG)-positive ...
T. Oluwole, A. Fowotade, D. Mirchandani, S. Almeida, K.S. Plante, S. Weaver, R. Bakare   +6 more
doaj   +1 more source