Results 51 to 60 of about 3,621,615 (290)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Relationship of β-casein genotypes (A1A1, A1A2 and A2A2) to the physicochemical composition and sensory characteristics of cows’ milk

Journal of Applied Animal Research, 2022
This study determines the relationship between β-casein CSN2 genotypes (A1A1, A1A2, A2A2) and milk’s biochemical and sensory traits. Ninety-six cow’s milk from the same herd was investigated.
Kristina de Vitte, Sigita Kerziene, Jolita Klementavičiūtė, Marius de Vitte, Ramutė Mišeikienė, Ieva Kudlinskienė, Justė Čepaitė, Vaida Dilbiene, Rolandas Stankevičius   +8 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Chromaticity Study of Yellow HTHP Lab-Grown Diamonds Based on Spectroscopy

Crystals
In recent years, lab-grown diamonds have become more popular in both domestic and international markets for their rich color palette. Research on yellow lab-grown diamonds has primarily focused on spectroscopic and defect characteristics currently, while
Zhuchun Peng, Yicong Sun, Mingming Xie, Zheng Zhang, Bin Meng, Siqi Yang, Endong Zu   +6 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The effect of various nickel oxide ratios on the color and reflectivity of PY53 nickel-titanate yellow pigment

Results in Chemistry, 2022
Complex inorganic nickel-titanate PY53 yellow pigments with a high thermal solar reflectance were synthesized. Four different compositions were made with increasing nickel oxide (NiO) ratios, with Sb2 O3 and TiO2 as the fixed components.
Emre Aslan, Emre Toy, Zeynep Güner, Alejandro Grijalbo, Emine Yeşilci, Buğra Çiçek   +5 more
doaj   +1 more source

Indexing of Yellow Vein Mosaic Disease of Mesta (Hibiscus cannabinus)

Pakistan Journal of Biological Sciences, 2013
The assessment of severity with chronological development of disease of mesta (Hibiscus cannabinus, cv. HC-583) on a particular diseased plant was studied. Based on the symptomatology and intensity of diseases caused by Begomovirus an empirical formula was developed.
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source