Results 71 to 80 of about 3,621,615 (290)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 1970 This is the College of Wooster yearbook from 1970. The Index focuses on student life, depicting different events on campus. Most of the pages are filled with more photos than text illustrating these events.
Editors, Index, Index Editors,
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Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
, 2009 This is the College of Wooster Index from 2009. The sections of the Index include Student Life, Politics, Sports, Seniors, and Organizations. The Index also features information about renovations of Beall Ave.
Editors, Index
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Influence of process parameters on the energy requirements and dried sliced tomato quality
Engineering Reports, 2020 This study presents the effects of process parameters on the energy demand for drying and quality indices of dried tomato slices. The experiment was designed and analyzed with the Box‐Behnken method of Design Expert and conducted for drying 1800 g batch ...
Nnaemeka R. Nwakuba +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Photo-aging changes in mechanical properties of high impact polystyrene, polystyrene-based binary and compatibilized ternary blends [PDF]
Polyolefins JournalIn this work, the photo-aging behavior of high impact polystyrene (HIPS), polystyrene/ethylene propylene diene monomer (PS/EPDM) binary blends, and compatibilized polystyrene/ethylene propylene diene monomer/ polyamide 6 (PS/EPDM/PA6) ternary blends was ...
Marzieh Alidadi-Shamsabadi +3 more
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
, 1976 This is the 1976 edition of the Index. The Index is written by student editors, and it is the college’s yearbook. It includes an annual record of events at Wooster. The first few pages of this Index is a memoriam dedication.
Index Editors,
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