Results 61 to 70 of about 10,569 (182)

Caenorhabditis elegans bacterial pathogen resistant bus-4 mutants produce altered mucins.

PLoS ONE, 2014
Caenorabditis elegans bus-4 glycosyltransferase mutants are resistant to infection by Microbacterium nematophilum, Yersinia pestis and Yersinia pseudotuberculosis and have altered susceptibility to two Leucobacter species Verde1 and Verde2. Our objective
Lisa M Parsons, Rahman M Mizanur, Ewa Jankowska, Jonathan Hodgkin, Delia O Rourke, Dave Stroud, Salil Ghosh, John F Cipollo   +7 more
doaj   +1 more source

An RNA thermometer dictates production of a secreted bacterial toxin.

PLoS Pathogens, 2020
Frequent transitions of bacterial pathogens between their warm-blooded host and external reservoirs are accompanied by abrupt temperature shifts. A temperature of 37°C serves as reliable signal for ingestion by a mammalian host, which induces a major ...
Christian Twittenhoff, Ann Kathrin Heroven, Sabrina Mühlen, Petra Dersch, Franz Narberhaus   +4 more
doaj   +1 more source

Developmental Impact of Maternal Immune Activation on the Fetal Immune System and Lung

European Journal of Immunology, Volume 56, Issue 1, January 2026.
Maternal immune activation triggers elevated cytokines (IL‐6 and IL‐17A), disrupting fetal immune system development. This not only alters hematopoietic stem cell balance but also leads to ILC2 hyperactivation in the lung, which could potentially affect susceptibility to allergic diseases in the offspring.
Walaa Jradi, Kira Duhm, Clarissa Prazeres da Costa   +2 more
wiley   +1 more source

Interaction of Staphylococcus aureus di‐iron Repair of Iron Centers protein with the iron–sulfur cluster assembly SUF system

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Repair of Iron Centers (RIC) proteins are present in several pathogens, including Staphylococcus aureus, contributing to resistance to nitroxidative stress and virulence. In this work, we investigated the molecular mechanisms by which S. aureus RIC facilitates iron mobilization, through structural analyses and functional studies.
Frederico M. Lourenço, Liliana S. O. Silva, Mafalda R. Almeida, Filipe Folgosa, Pedro M. Matias, Sandra M. Carvalho, João C. Lima, Célia V. Romão, Lígia M. Saraiva   +8 more
wiley   +1 more source

Foci of yersiniosis infections in the Crimean Peninsula

Журнал микробиологии, эпидемиологии и иммунобиологии
Introduction. A significant increase in morbidity and a high rates of infection among small mammals in a number of areas have determined a significant worsening of the epidemiological situation with yersiniosis. Objective.
Elena V. Bednarskaya, Nataliia B. Dmitrencko, Nataliia A. Berkovich, Roman V. Proskurnin   +3 more
doaj   +1 more source

Overlap of rheumatoid arthritis flare and Yersinia-induced reactive arthritis: A clinical case and literature review

Annales Academiae Medicae Silesiensis
Yersiniosis is a zoonotic bacterial disease caused by Yersinia enterocolitica (Y. enterocolitica) and Yersinia pseudotuberculosis, which can lead to the development of extraintestinal inflammatory complications, including reactive arthritis.
Aleksandra Guzowska, Olivier Połeć, Ewa Pękala, Agata Stanek   +3 more
doaj   +1 more source

Expansion of CD101⁻ neutrophils drives susceptibility to hyperyersiniabactin-producing Yersinia infection in hereditary hemochromatotic hosts

Infection and Immunity
Hereditary hemochromatosis (HH) increases susceptibility to bacterial infections. In our previous study, an oral Yersinia pseudotuberculosis Δfur mutant (Δfur) infection led to intestinal barrier disruption and acute mortality in HH (Hfe−/−) mice ...
Shreya Das, Saugata Majumder, Mohd Saqib, McKenzie Van der Veer, Bossardi Ramos Ramon, Akaki Tsilosani, Wenzheng Zhang, Qi Yang, Sridar V. Chittur, Wei Sun   +9 more
doaj   +1 more source

Concerted actions of a thermo-labile regulator and a unique intergenic RNA thermosensor control Yersinia virulence.

PLoS Pathogens, 2012
Expression of all Yersinia pathogenicity factors encoded on the virulence plasmid, including the yop effector and the ysc type III secretion genes, is controlled by the transcriptional activator LcrF in response to temperature.
Katja Böhme, Rebekka Steinmann, Jens Kortmann, Stephanie Seekircher, Ann Kathrin Heroven, Evelin Berger, Fabio Pisano, Tanja Thiermann, Hans Wolf-Watz, Franz Narberhaus, Petra Dersch   +10 more
doaj   +1 more source

Species distribution and antimicrobial susceptibility of gram-negative aerobic bacteria in hospitalized cancer patients

Journal of Translational Medicine, 2009
Background Nosocomial infections pose significant threats to hospitalized patients, especially the immunocompromised ones, such as cancer patients. Methods This study examined the microbial spectrum of gram-negative bacteria in various infection sites in
El-Sharif Amany, Ashour Hossam M
doaj   +1 more source

Mechanistic insights into the orthogonal functionality of an AHL-mediated quorum-sensing circuit in Yersinia pseudotuberculosis

Synthetic and Systems Biotechnology
YpsR, a pivotal regulatory protein in the quorum-sensing (QS) of Yersinia pseudotuberculosis(Y. pstb), is essential for molecular signaling, yet its molecular mechanisms remain poorly understood.
Boyu Luo, Shanshan Wu, Wei Liu, Dongdong Zhang, Ruicun Liu, Tuoyu Liu, Zhi Sun, Ziqun Wei, Mingyu Liu, Zhiyuan Shi, Niu Huang, Yue Teng   +11 more
doaj   +1 more source