Efficient Synthesis of Fused Polycyclic Ether Systems via Sulfonium Ylides: A Synthetic Approach to Yessotoxin and Adriatoxin [PDF]
Marine DrugsA novel class of chiral sulfonium salts, derived from L- and D-methionine, was designed and successfully employed for the diastereoselective synthesis of epoxy amides.
Federico Moya-Utrera +4 more
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Optimization and Validation of a High Throughput UHPLC-MS/MS Method for Determination of the EU Regulated Lipophilic Marine Toxins and Occurrence in Fresh and Processed Shellfish [PDF]
Marine Drugs, 2022 Under the name of lipophilic marine toxins, there are included more than 1000 toxic secondary metabolites, produced by phytoplankton, with the common chemical property of lipophilicity.
Teresa D’Amore +3 more
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Dissolved Algal Toxins along the Southern Coast of British Columbia Canada [PDF]
Toxins, 2023 Harmful algal blooms (HABs) in coastal British Columbia (BC), Canada, negatively impact the salmon aquaculture industry. One disease of interest to salmon aquaculture is Net Pen Liver Disease (NPLD), which induces severe liver damage and is believed to ...
Ryan B. Shartau +6 more
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Initial refinement of data from video‐based single‐cell tracking [PDF]
Cancer Innovation, 2023 Background Video recording of cells offers a straightforward way to gain valuable information from their response to treatments. An indispensable step in obtaining such information involves tracking individual cells from the recorded data.
Mónica Suárez Korsnes, Reinert Korsnes
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Integrated Multi-Omics Analysis Reveals Complex Cytotoxicity-Associated Molecular Response Patterns of Representative Toxins from Four Classes of Lipophilic Algal Toxins in Neuro-2a Cells [PDF]
ToxinsLipophilic marine toxins (LMTs) are important toxic risk factors in marine ecosystems and seafood safety, yet the comparative cytotoxicity-associated molecular responses of different LMT classes remain unclear.
Xueru Wei +5 more
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The Bayesian β-binomial model to improve the inference based on the results of sampling plans: the case study of the biotoxin monitoring plan of Chamelea gallina natural beds [PDF]
Italian Journal of Food SafetySampling is a cornerstone of food safety monitoring, yet traditional frequentist approaches can yield unreliable inferences in the presence of rare or absent events, particularly when maximum likelihood estimates lie on the boundary of the parameter ...
Cesare Ciccarelli +7 more
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Yessotoxin, a Promising Therapeutic Tool
Marine Drugs, 2016 Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second
Mercedes Rodriguez Vieytes +2 more
exaly +3 more sources
Effects of okadaic acid, azaspiracid-1, yessotoxin and their binary mixtures on human intestinal Caco-2 cells [PDF]
EXCLI Journal : Experimental and Clinical SciencesPhycotoxins are responsible for foodborne intoxications. Symptoms depend on the ingested toxins but mostly imply gastro-intestinal and neurological disorders.
Jimmy Alarcan, Albert Braeuning
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Decoding the therapeutic mechanism of Conocarpus lancifolius in hepatocellular carcinoma: network pharmacology, molecular docking, and LC-MS QTOF insights [PDF]
Frontiers in PharmacologyHepatocellular carcinoma is a multifaceted and lethal malignancy, ranking third in cancer-related mortality and sixth in worldwide incidence. This study aimed to utilize LCMS-QTOF analysis to identify the phytoconstituents of C.
Poojaben M. Prajapati +6 more
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Deep Turbulence as a Novel Main Driver for Multi-Specific Toxic Algal Blooms: The Case of an Anoxic and Heavy Metal-Polluted Submarine Canyon That Harbors Toxic Dinoflagellate Resting Cysts [PDF]
MicroorganismsOver the recent decades, an apparent worldwide rise in Harmful Algae Blooms (HABs) has been observed due to the growing exploitation of the coastal environment, the exponential growth of monitoring programs, and growing global maritime transport.
Camilo Rodríguez-Villegas +11 more
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