Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Feasibility of using a patient portal to recruit Latino adults into a smoking cessation and physical activity randomized clinical trial: A secondary analysis. [PDF]
Uceda VC +17 more
europepmc +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Assisted evolution of corals and their symbionts enhances recruit heat tolerance but with complex outcomes. [PDF]
Lamb AM +6 more
europepmc +1 more source
A Data-Driven Methodological Framework for Representative Recruitment in Psychiatric Research: Insights from the DOCUMENT Study [PDF]
Gooddy BJM +22 more
europepmc +2 more sources
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Aspergillus niger ZJ-17 enhances the yield and quality of Angelica dahurica var. formosana by modulating beneficial rhizobacteria: a sustainable strategy for plant production. [PDF]
Jiang M +9 more
europepmc +1 more source
The brownbanded bamboo shark (Chiloscyllium punctatum) is a benthic shark species distributed in Southeast Asia. The species has been listed as “Near Threatened” by the IUCN, but only based on indirect information. In this study, yield per recruit (YPR) and spawning per recruit (SPR) analyses were conducted to determine the current stock status.
openaire +1 more source
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Sediment burial reduces coral larval settlement, recruit survivorship, and inhibits the recovery of coral populations. [PDF]
Rodriguez-Ruano V +10 more
europepmc +1 more source

