Results 151 to 160 of about 6,822,950 (366)

Soil and Water Conservation Engineering Techniques to Modify the Rhizosphere Climate of Cucumber (Cucumis Sativus L.) for Improving Water Use Efficiency and Yield [PDF]

, 2022
Mallapurath Narayanamangalam Harinarayanan, Subbiah Ramanatha, Karuppalaki Nagarajan, Muthusamy Karuppusamy Kalarani, N. K. Sathyamoorthy, Indran Geethalakshmi, Sundarapandian Ramya   +6 more
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

458. Molecular Engineering of Adeno-Associated Virus Yields a Novel Variant with Efficient Intravitreal Transduction of Müller Cells [PDF]

, 2009
R. R. Klimczak, Deniz Dalkara, James T. Koerber, Kathleen D. Kolstad, David V. Schaffer, John G. Flannery   +5 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations [PDF]

, 2010
Debra Toiber, Garikoitz Azkona, Shani Ben‐Ari, Núria Torán, Hermona Soreq, Mara Dierssen   +5 more
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Predicting resprouting of Platanus × hispanica following branch pruning by means of machine learning

Frontiers in Plant Science
IntroductionResprouting is a crucial survival strategy following the loss of branches, being it by natural events or artificially by pruning. The resprouting prediction on a physiological basis is a highly complex approach. However, trained gardeners try
Qiguan Shu, Hadi Yazdi, Thomas Rötzer, Ferdinand Ludwig   +3 more
doaj   +1 more source

Regional Effects of Enzymatic Digestion on Knee Meniscus Cell Yield and Phenotype for Tissue Engineering [PDF]

, 2011
Johannah Sanchez‐Adams, Kyriacos A. Athanasiou   +1 more
openalex   +1 more source

Fluid dynamic-based Engineering design of a Full-Scale Device for the improvement of Extra Virgin Olive Oil Yield and Quality by means of Combined Acoustic Cavitation and Thermal Conditioning [PDF]

, 2020
Riccardo Amirante, Elia Distaso, Paolo Tamburrano, Filomena Faustina Rina Corbo, G. Calò, Maria Lisa Clodoveo   +5 more
openalex   +1 more source