Results 151 to 160 of about 436,262 (255)

Photocatalytic CO₂ reduction to methanol: from mechanistic insights to reactor design integration. [PDF]

RSC Adv
Zuo C, Wang J, Xin C, Su Q.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Explainable machine learning reveals diverse yield-determining factors among Thai rice farmer cohorts: Implications for targeted agricultural support. [PDF]

PLoS One
Suriyalaksh M, Prommawin B, Hannanta-Anan P, Sreewongchai T, Promchote P, Nakasathien S.   +5 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Ductile and scalable 3 GPa steel via a hierarchical microstructural architecture. [PDF]

Nat Commun
Geng R, Liu Y, Tang P, Yuan X, Li L, Liu Y, Wang H, Zheng L, Lei S, Sun Y, Cao Y, Li X, Han S, Li Y, Ritchie RO, Zhao S, Xu H, Wang C.   +17 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Enzyme-constrained genome-scale modeling resolves growth-production trade-offs in fermentative biohydrogen production. [PDF]

Environ Sci Ecotechnol
Xing W, Liu J, Liu B, Hou Y, Zhang J, Gao S, Wang AJ, Yuan Q, Ren NQ, Huang C.   +9 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Multi-Objective AI Optimization of Plastic Waste Pyrolysis Integrating Energy Return on Investment for Circular Polymer Recycling. [PDF]

Polymers (Basel)
Khanna A, Lamba BY, Jain S, Sah A, Dangi S, Sharma A, Tiang JJ, Tiang SS, Lim WH.   +8 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source