Results 121 to 130 of about 44,314 (257)

Stock assessment of elasmobranch in Southeast Asia using yield per recruit and spawning per recruit analyses [an abstract of dissertation and a summary of dissertation review]

open access: yesStock assessment of elasmobranch in Southeast Asia using yield per recruit and spawning per recruit analyses [an abstract of dissertation and a summary of dissertation review]
(主査) 教授 今村 央, 教授 髙津 哲也, 准教授 John Richard Bower, 教授 松石 隆(国際食資源学院) 水産科学院(海洋生物資源科学専攻)
openaire   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Tunas, yield per recruit and MSY of longline fisheries, case of the yellowfin stock in the Eastern Pacific ocean.

open access: yes, 2011
This paper discusses the conclusion of various IATTC stock assessment report on yellowfin that MSY of the longline fishery could be larger than 400000 t. in the EPO. Based on the analysis of fishery data and environmental data in the Pacific ocean and in the EPO, the paper reaches the conclusion that the real potential MSY of longliners on the EPO YFT ...
/Fonteneau, Alain, Ariz, J.
openaire   +3 more sources

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

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