Results 91 to 100 of about 4,436,723 (262)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Integrating crop modeling and climate projections to evaluate cotton yield response to tillage and cover crops in the Southeastern US

open access: yesTechnology in Agronomy
Climate change poses a significant threat to cotton production in the Southeastern United States, necessitating adaptive management strategies that enhance yield stability and system resilience.
Pourebrahimi Foumani Mohil   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Mutation Breeding as a Tool for Sustainable Crop Production and Climate Resilience: Experiences from the South-Eastern Europe (SEE) and Central Asia (CA)

open access: yesAgronomy
The review summarizes practical experiences in using mutation breeding for crop improvement in South-Eastern Europe (SEE) and Central Asia (CA), demonstrating that mutation breeding can be a field-validated, effective approach for developing climate ...
Sandra Cvejić   +35 more
doaj   +1 more source

Assessment of yield stability in sugarcane genotypes using non-parametric methods [PDF]

open access: yes, 2015
The evaluation of performance stability and high yields is essential for yield trials in different environments. This study was carried out to identifysugarcane genotypesthat have both a high mean cane yield, mesured in tons of cane per hectare (TCH ...
Ramón, Miguel   +13 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

BRS FC402: high-yielding common bean cultivar with carioca grain, resistance to anthracnose and fusarium wilt

open access: yesCrop Breeding and Applied Biotechnology, 2017
BRS FC402 is a common bean cultivar of the carioca-grain group with commercial grain quality, suitable for cultivation in 21 Brazilian states. Cultivar has a normal cycle (85-94 days), high yield potential (4479 kg ha-1), 10.1% higher mean yield than the
Leonardo Cunha Melo   +10 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Integrated Organic–Inorganic Fertilizer Management: Enhancing Crop Productivity, Soil Health, and Greenhouse Gas Mitigation

open access: yesAgronomy
Integrated nutrient management (INM) is increasingly recognized as a promising approach for sustaining crop productivity while reducing some of the environmental impacts associated with intensive agricultural production.
Mubarak Ado Abdullahi   +3 more
doaj   +1 more source

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