Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Agro-morphological performance, nutritive value and dry matter yield stability of mission grass (Pennisetum polystachion (L.) Schult) genotypes in multi-environment trials in Western Oromia, Ethiopia. [PDF]
Wekgari Y, Dereba F.
europepmc +1 more source
Evaluation of grain yield stability of tritipyrum as a novel cereal in comparison with triticale lines and bread wheat varieties through univariate and multivariate parametric methods. [PDF]
Farokhzadeh S +3 more
europepmc +1 more source
Formation mechanism of yield stability in high-yielding rapeseed varieties
openaire +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Publisher Correction: Analysis of yield stability and genotype-environment interaction for open-pollinated tomato varieties in the Kashmir Himalaya using the AMMI model. [PDF]
Masoodi UH +6 more
europepmc +1 more source
Reduced basal and increased topdressing fertilizer rate combined with straw incorporation improves rice yield stability and soil organic carbon sequestration in a rice-wheat system. [PDF]
Zhang J +9 more
europepmc +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Multi-environment field trials for wheat yield, stability and breeding progress in Germany. [PDF]
Wang TC +13 more
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source

