Results 101 to 110 of about 519,262 (262)

Consistency and Rheological Properties of Cemented Paste Backfills Prepared with Tailings with Varying Free Muscovite Content

Mining
The presence of free muscovite in tailings can negatively affect the mechanical strength and rheological properties of cemented paste backfill, as has been observed for several cementitious materials. The aim of this study is to evaluate the influence of
Hadj Ghani Menasria, Mamert Mbonimpa, Tikou Belem, Abdelkabir Maqsoud   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Limit of the Greatest Stress at the Yield Point

Transactions of the Society of Mechanical Engineers, 1935
軟鋼の降伏は一種の安定の問題であつて、或る断面に降伏が起るとすればその面の全体の内力分布状態を考慮に入れなければならないことは既に屡述べたし、また実際安定の毀れるところで必ず降伏の起ることも既に種々の実驗によつて確めた。然るにこれ以外にも降伏を起す場合がありさうである。と云ふのは或る局部にだけ大きな内力の働いてゐる場合等は全体の安定は中々毀れなければ最大内力は何處までゞも大きくなり得るであらうか。材料の性質として何處かに限界がありさうに思ふ。距形柱体の捩り試驗を行つて見た結果、この剪断内力の限界値は1.5τyと出て耒た。茲にτyは均等内力の下に降伏するときの剪断内力であつて材料によつて定まつた値である。二次元の問題のときには何時もこの1.5τyと云ふのが限界値であるやうに思ふ ...
openaire   +2 more sources

Foam coarsening in a yield stress fluid

Soft Matter
Foams made from emulsion show heterogeneous bubble organisation and growth during coarsening due to the continuous phase yield stress.
Alice Requier, Chiara Guidolin, Emmanuelle Rio, Nicolò Galvani, Sylvie Cohen-Addad, Olivier Pitois, Anniina Salonen   +6 more
openaire   +3 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Yield-stress transition in suspensions of deformable droplets. [PDF]

Sci Adv, 2023
Negro G, Carenza LN, Gonnella G, Mackay F, Morozov A, Marenduzzo D.   +5 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source