Results 171 to 180 of about 519,262 (262)

Ultraviolet-Follow Curing-Mediated Extrusion Stabilization for Low-Yield-Stress Silicone Rubbers: From Die Swell Suppression to Dimensional Accuracy Enhancement. [PDF]

Polymers (Basel)
Liu B, Ma B.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

The grouting plugging mechanism of layered jointed rock mass considering the time-varying yield stress of grout. [PDF]

Sci Rep
Yalei Z, Kepeng H, Zongyong W, Shifei Y, Yunlin Y, Yong Y.   +5 more
europepmc   +1 more source

Mastering Yield Stress Evolution and Formwork Friction for Smart Dynamic Casting. [PDF]

Materials (Basel), 2020
Szabo A, Reiter L, Lloret-Fritschi E, Gramazio F, Kohler M, Flatt RJ.   +5 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Effect of the Drying Method of Pine and Beech Wood on Fracture Toughness and Shear Yield Stress. [PDF]

Materials (Basel), 2020
Chuchala D, Sandak J, Orlowski KA, Muzinski T, Lackowski M, Ochrymiuk T.   +5 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Modeling SAOS Yield Stress of Cement Suspensions: Microstructure-Based Computational Approach. [PDF]

Materials (Basel), 2020
Ukrainczyk N, Thiedeitz M, Kränkel T, Koenders E, Gehlen C.   +4 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source