Results 161 to 170 of about 576,522 (312)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Heat and drought stress on durum wheat: Responses of genotypes, yield, and quality parameters
, 2013 Heat and/or drought stress during cultivation are likely to affect the processing quality of durum wheat (Triticum turgidum L ssp. durum). This work examined the effects of drought and heat stress conditions on grain yield and quality parameters of nine ...
Pena, Roberto J. +4 more
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, 2009 The behaviour of viscoplastic drops during formation and detachment from a capillary nozzle, free-fall, impact on a solid substrate and subsequent spreading are investigated experimentally by high-speed imaging.
German, Guy, Guy German
core
Research on the Relation between Slump Flow and Yield Stress of Ultra-High Performance Concrete Mixtures. [PDF]
Materials (Basel), 2022 Liu J, An M, Wang Y, Han S, Yu Z.
europepmc +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Regional similarities in the distributions of well yield from crystalline rocks in Fennoscandia [PDF]
, 2010 Well yields from Precambrian and Palaeozoic bedrock in Norway, Sweden and Finland exhibit very similar and approximately log-normal distributions: all three data sets exhibit a median yield of 600–700 L hr-1, despite the differences in climate and ...
Gustafson, G. +4 more
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MaCts1, an Endochitinase, Is Involved in Conidial Germination, Conidial Yield, Stress Tolerances and Microcycle Conidiation in Metarhizium acridum. [PDF]
Biology (Basel), 2022 Zou Y, Li C, Wang S, Xia Y, Jin K.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Printable and Conductive Yield-Stress Fluid as an Ultrastretchable Transparent Conductor. [PDF]
Research (Wash D C), 2021 Lu Q +5 more
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source