Results 151 to 160 of about 1,437,909 (339)

Effect of Farming System and Irrigation on Nutrient Content and Health-Promoting Properties of Carrot Roots

open access: yesAgronomy
The field experiment on growing carrots included I. an organic system without pesticides and mineral fertilization of NPK; a conventional system involving NPK fertilization and pesticides in 100% doses; an integrated system, with doses of NPK and ...
Elżbieta Harasim   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Plonowanie i zachwaszczenie ziemniaka w warunkach zróżnicowanego poziomu agrotechniki na glebie lekkiej

open access: yesAgronomy Science, 2003
A strict field experiment was conducted at the Experimental Farm Uhrusk, a part of the Agricultural University in Lublin in the years 1995-1997. The experiment was set on the podzolic soil formed from coarse sandy soils, a good rye complex.
Stanisław Deryło   +1 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

THE EFFECT OF ROOTSTOCK ON THE GROWTH AND YIELDING OF CULTIVAR ‘KORDIA’ SWEET CHERRY TREES

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2008
The studies conducted in the years 2004–2006 in a production orchard in the habitat conditions of the Sandomierska Upland showed that the trees budded on the seedlings of wild cherry grew more strongly than on Colt rootstock.
Stanisław Wociór
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Analysis model of yielding components.

open access: yes
In solving the whole process of interaction between soft rock and yielding support in high-stress environments in tunnels using mechanical analysis methods, it is challenging to simultaneously satisfy both displacement coordination and static equilibrium
Biao Dong (519216)   +2 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

EFFECT OF ORGANIC-MINERAL FERTILIZERS ON THE YIELD AND QUALITY OF ENDIVE (Cichorium endivia L.)

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2012
Endive is a leaf vegetable, not commonly known in Poland, although popular in Western and Southern Europe. It deserves attention because of its high nutritive value and bitter taste caused by sesquiterpene lactones. In the experiments carried out in the
Janina Gajc-Wolska   +4 more
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy