Results 101 to 110 of about 1,214,521 (291)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Rendimiento de materia seca y otros componentes en Leucaena leucocephala cv. Cunningham con el uso del Liplant

open access: yesPastos y Forrajes
En la Universidad Agraria de La Habana se producen bioestimuladores que han sido empleados con éxito en la producción agrícola de diferentes especies de plantas.
Hilda B Wencomo, Yudith Lugo
doaj  

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Определяне на равнището на азотно торене при двуоткосно прибиране на зимна грахово-тритикалена смеска за производство на фураж

open access: yesПочвознание, агрохимия и екология, 2012
The influence of nitrogen fertilization on the productivity of forage апа crude protein of winter pea-triticale mixture during two-cut harvesting crops was studied. The experiment was conducted with winter forage pea variety “Mir” and triticale variety “
ТОДОР КЕРТИКОВ   +1 more
doaj  

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Down-regulation of GhADF1 in cotton (Gossypium hirsutum) improves plant drought tolerance and increases fiber yield

open access: diamond, 2022
Lixia Qin   +6 more
openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Genotypes of Sechium spp. as a Source of Natural Products with Biological Activity

open access: yesLife
The genus Sechium P. Br. (Cucurbitaceae) includes ten species, two of which are edible. The inedible genotypes are in a fragile ecological niche, since they are not used by rural inhabitants. A rescue and genetic crossing program was designed to identify
Jorge Cadena-Iñiguez   +9 more
doaj   +1 more source

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