Bridging Breeds: Transcriptomic Insights into Immune Traits of Yili, Thoroughbred, and Kazakh Horses [PDF]
LifeBackground: Studying the genetic characteristics and molecular mechanisms of immune regulation in horses is of great significance for protecting their genetic resources, improving breeding strategies, and enhancing their disease resistance, thereby ...
Tongliang Wang +7 more
doaj +5 more sources
Integrated targeted metabolomics and transcriptomics analysis reveals heterogeneity of subcutaneous and pericardial adipose tissues in Yili horses [PDF]
Food Chemistry: Molecular SciencesFat deposition is a key economic trait in livestock, yet distinct adipose depots often display marked functional heterogeneity. The molecular basis underlying this divergence in Yili horses, however, remains poorly understood.
Liping Yang +8 more
doaj +5 more sources
Lipidomics and biochemical profiling of adult Yili horses in a 26 km endurance race: exploring metabolic adaptations [PDF]
Frontiers in Veterinary ScienceThe equine lipid metabolism is activated during and after endurance exercise to provide energy in response to the metabolic and physiological changes in the body caused by prolonged exercise; however, the specific regulatory mechanisms remain ...
Xiaokang Chang +9 more
doaj +6 more sources
Absolute Quantitative Lipidomics Reveals Differences in Lipid Compounds in the Blood of Trained and Untrained Yili Horses [PDF]
Veterinary SciencesThe purpose of this study was to explore the relationship between blood lipid levels and the differences in cardiac structure and function of trained and untrained Yili horses as related to exercise performance.
Tongliang Wang +8 more
doaj +5 more sources
Plasma Lipidomics and Proteomics Analyses Pre- and Post-5000 m Race in Yili Horses [PDF]
AnimalsThe impact of exercise on human metabolism has been extensively studied, yet limited research exists on the effects of high-intensity racing on equine metabolism.
Jianwen Wang +8 more
doaj +5 more sources
Integrating miRNA, mRNA, and Targeted Metabolomics Analyses to Explore the Regulatory Mechanism of Cardiac Remodeling in Yili Horses [PDF]
BiologyTraining not only enhances the athletic performance of horses but also improves cardiac structure and function, strengthens cardiovascular adaptability, and reduces the risk of cardiovascular diseases.
Tongliang Wang +8 more
doaj +5 more sources
Genome-Wide DNA Methylation Analysis of Performance Variation in the 5000-m Speed Race of Yili Horses [PDF]
AnimalsWhole-genome bisulfite sequencing (WGBS) was employed in this article to map blood DNA methylation profiles at single-base resolution in Yili horses before a 5000 m speed race, with comparative analysis of epigenetic differences between the ‘elite group’
Dehaxi Shan +9 more
doaj +6 more sources
Effects of Different Stages of Training on the Intestinal Microbes of Yili Horses Analyzed Using Metagenomics [PDF]
GenesObjectives: The aim of this study was to investigate the effects of different stages of training on the intestinal microbial abundance of Yili horses.
Xin-Kui Yao
exaly +5 more sources
The Effect of Training on the Expression of Protein and Metabolites in the Plasma Exosomes of the Yili Horse [PDF]
AnimalsObjective: The effects of physical exercise on protein expression and metabolites in the plasma exosomes of Yili horses are not yet clear. This study aims to elucidate the effects of exercise training on the expression of plasma extracellular vesicle ...
Xinxin Yuan +9 more
doaj +4 more sources
Comparative analysis of miRNA expression in Yili horses pre- and post-5000-m race [PDF]
Frontiers in GeneticsEquine athletic performance is modulated by both genetic and epigenetic mechanisms. As dynamic regulators of gene expression, MicroRNAs (miRNAs) play a central role in the physiological response to exercise-induced stress18. This study focused on the top
Shikun Ma +10 more
doaj +4 more sources