The Yolk Sac Feeds Pancreatic Tumors [PDF]
In this issue of Immunity, Zhu et al. (2017) report that tumor-associated macrophages in a mouse model of pancreatic ductal adenocarcinoma (PDAC) originate from both the yolk sac (YS) and bone marrow. Differential ablation of these populations indicates that only the YS-derived macrophages promote PDAC progression and growth.
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Trpm2 partial and complete knockout reduce neuroinflammation in male and female mice. Microglial morphological changes are not found in Trpm2 knockout 6‐OHDA‐induced mice. TRPM2 is involved in microglial phagocytosis and IL1β, IL6, and iNOS expression. ABSTRACT Inflammation, and particularly microglial cells, has become a central feature in Parkinson's
Ana Flávia F. Ferreira+3 more
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ELECTRON MICROSCOPIC OBSERVATIONS OF THE DEVELOPMENT OFCOXIELLA BURNETIIIN THE CHICK YOLK SAC [PDF]
R. L. Anacker+3 more
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Diagnosis and management of gestational trophoblastic disease: 2025 update
Abstract Gestational trophoblastic disease (GTD) arises from abnormal placenta and comprises a spectrum of premalignant to malignant disorders. Changes in the epidemiology of GTD have been noted in various countries. In addition to histology, molecular genetic studies can help in the diagnostic pathway.
Hextan Y. S. Ngan+7 more
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Alpha-fetoprotein and germ cell tumors: A possible role of yolk sac tumor in production of alpha-fetoprotein [PDF]
Aleksander Talerman, W. G. Haije
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This study investigates the vertical transmission of maternal microbiota in chickens and how it is modulated by maternal soyasaponin supplementation. Using a model spanning the reproductive tract, egg components, and developing chicks, we show that maternal gut and reproductive microbiota, including Bifidobacterium adolescentis (B.
Mingkun Gao+10 more
wiley +1 more source
Are Abnormal Yolk Sac Characteristics Important Factors in Abortion Rates? [PDF]
Background This study was undertaken to determine if there were different abortion rates between normal and abnormal yolk sacs. Materials and Methods In this cohort study, the yolk sac characteristics of 193 consecutive pregnant women, of 5-6.5 ...
Sanam Moradan, Mohammad Forouzeshfar
doaj
Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro+6 more
wiley +1 more source
Serum alphafetoprotein (AFP) in diagnosis and management of endodermal sinus (yolk sac) tumor and mixed germ cell tumor of the ovary [PDF]
Aleksander Talerman+2 more
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Quantitative studies of pinocytosis. II. Kinetics of protein uptake and digestion by rat yolk sac cultured in vitro. [PDF]
Kenneth E. Williams+3 more
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