Results 131 to 140 of about 78,011 (319)

Serum alphafetoprotein (AFP) in diagnosis and management of endodermal sinus (yolk sac) tumor and mixed germ cell tumor of the ovary [PDF]

, 1978
Aleksander Talerman, W. G. Haije, L. Baggerman   +2 more
openalex   +1 more source

Prematurely Aged Human Microglia Exhibit Impaired Stress Response and Defective Nucleocytoplasmic Shuttling of ALS Associated FUS

Aging Cell, EarlyView.
We developed a human microglia aging model by doxycycline‐induced GFP‐progerin expression, which offers a valuable tool to study human microglial aging and its contribution to neurodegeneration. Induced HMC3‐Progerin cells exhibited increased age markers as well as transcriptomic alterations, including an age‐associated transcriptomic shift and ...
Christiane Hartmann, Christina Haß, Muriel Knobloch, Israel Barrantes, Laura Fumagalli, Jessie Premereur, Franz Markert, Maite Peters, Georgia Koromila, Alexander Hartmann, Kathrin Jäger, Jette Abel, Renzo Mancuso, Alexander Storch, Michael Walter, Georg Fuellen, Andreas Hermann   +16 more
wiley   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

The Human Yolk Sac and Yolk Sac Tumors [PDF]

Journal of Clinical Pathology, 1994
openaire   +2 more sources

HoxA3 is an apical regulator of haemogenic endothelium. [PDF]

, 2011
During development, haemogenesis occurs invariably at sites of vasculogenesis. Between embryonic day (E) 9.5 and E10.5 in mice, endothelial cells in the caudal part of the dorsal aorta generate haematopoietic stem cells and are referred to as haemogenic ...
Caprioli, Arianna, Chong, Diana, Cleaver, Ondine, Hartweck, Lynn, Iacovino, Michelina, Kyba, Michael, Rux, Danielle, Szatmari, Istvan   +7 more
core  

Immunofluo rescent demonstration of alpha-fetoprotein and other plasma proteins in yolk sac tumor [PDF]

, 1976
Toshikazu Shirai, Tetsuo Itoh, Takashi Yoshiki, Takashi Noro, Yasuhiko Tomino, Takashi Hayasaka   +5 more
openalex   +1 more source

Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours

Andrology, EarlyView.
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody, Daniela Fietz, Benedict Nathaniel, Mark Frydenberg, Ben Tran, Hans‐Christian Schuppe, Kate L. Loveland   +6 more
wiley   +1 more source

Zebrafish Xenograft Model for Predicting Cisplatin Efficacy in Muscle‐Invasive Bladder Cancer

Cancer Science, EarlyView.
This study establishes a zebrafish patient‐derived xenograft (zPDX) model optimized for predicting cisplatin sensitivity in muscle‐invasive bladder cancer. Through technical validation and correlation with clinical outcomes, the model demonstrated its potential as a rapid, cost‐effective platform for individualized chemotherapy response assessment ...
Yusuke Sugino, Xin Bao, Sho Sekito, Shiori Miyachi, Takumi Kageyama, Takeshi Sasaki, Kouhei Nishikawa, Toshio Tanaka, Manabu Kato, Yasuhito Shimada, Keishi Takano, Raku Son, Liqing Zang, Kenji Nakayama, Masatoshi Watanabe, Yasuhiro Murakawa, Takahiro Inoue   +16 more
wiley   +1 more source

Changes in gastrointestinal motility and gut hormone secretion after Roux‐en‐Y gastric bypass and sleeve gastrectomy for individuals with severe obesity

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Background Bariatric surgery is very effective in long‐term weight management. The present study was undertaken to investigate the short‐term effects of sleeve gastrectomy (SG) and of Roux‐en‐Y gastric bypass (RYGB) on (a) gastrointestinal (GI) motility, that is gastric emptying and oro‐cecal transit time and (b) secretion of regulatory gut ...
Jennifer A. Wilbrink, Mark van Avesaat, Simon W. Nienhuijs, Arnold Stronkhorst, Ad A. M. Masclee   +4 more
wiley   +1 more source

THE EFFECTS OF 5-BROMODEOXYURIDINE ON YOLK SAC ERYTHROPOIESIS IN THE CHICK EMBRYO [PDF]

, 1971
Yasusada Miura, Fred H. Wilt
openalex   +1 more source