Results 141 to 150 of about 75,211 (286)
A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics
Andrology, EarlyView.ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis +3 more
wiley +1 more source
Infection control in the brain and the eye
Acta Ophthalmologica, EarlyView.Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
The Embryonic Development of the Cotylean Polyclad Phrikoceros jannetae
Acta Zoologica, EarlyView.ABSTRACT Polyclads exhibit distinct developmental modes ranging from direct to indirect development, with several transitional stages also recognised. The existence of an indirect developmental mode in polyclads with a planktonic life history stage in the form of a free‐swimming larva is unique among all free‐living flatworms and makes polyclads a ...
Mehrez Gammoudi +6 more
wiley +1 more source
Cancer Science, EarlyView.This study provides the first comprehensive characterization of the functional impact, and mechanistic role of FAT4 in MM. Our findings highlight the tumor‐suppressive role of FAT4 in MM and uncover a novel mechanism by which FAT4 regulates the Hippo/YAP pathway.
Lina Zhang +5 more
wiley +1 more source
Clinical Obesity, Volume 15, Issue 2, April 2025.Summary Background Bariatric surgery is very effective in long‐term weight management. The present study was undertaken to investigate the short‐term effects of sleeve gastrectomy (SG) and of Roux‐en‐Y gastric bypass (RYGB) on (a) gastrointestinal (GI) motility, that is gastric emptying and oro‐cecal transit time and (b) secretion of regulatory gut ...
Jennifer A. Wilbrink +4 more
wiley +1 more source
Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss
Equine Veterinary Journal, EarlyView.Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez +6 more
wiley +1 more source
Offspring Size Resolves a Population Growth Paradox in Rays and Skates
Fish and Fisheries, EarlyView.ABSTRACT The maximum intrinsic population growth rate, rmax, is a key determinant of sustainable fishing limits and is increasingly used in risk assessments. We previously showed how the rmax of rays and skates (subclass Batoidea) scales with adult body size, temperature (and hence depth) such that smaller‐bodied species and those in warmer, shallower ...
Ellen Barrowclift +4 more
wiley +1 more source
Fish and Fisheries, EarlyView.The recent markedly reduced recruitment success (recruitment per spawner stock biomass) of Northeast Arctic cod (Gadus morhua, Gadidae) is seemingly largely attributed to the joint negative effect of increased temperature and cannibalism but also predation on the postlarvae by Northeast Atlantic mackerel (Scomber scombrus, Scombridae).
Shuyang Ma +11 more
wiley +1 more source
Fisheries Oceanography, EarlyView.ABSTRACT Yellowfin sole (Limanda aspera) support the largest flatfish fishery in the world and contribute substantially to the eastern Bering Sea (EBS) flatfish catch. The EBS has been warming and acidifying, trends that are expected to intensify into the future.
Emily Slesinger +5 more
wiley +1 more source